| Gene Symbol |
LRRC52
|
| Entrez Gene |
440699
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
leucine rich repeat containing 52
|
| Other Description |
BK channel auxiliary gamma subunit LRRC52|BK channel auxilliary gamma subunit LRRC52|leucine-rich repeat-containing protein 52
|
| Swissprots |
A2RUN7 Q8N7C0 Q5T9K5
|
| Accessions |
Q8N7C0 AA725678 AK098677 BAC05375 BC132981 AAI32982 BC132983 AAI32984 NM_001005214 NP_001005214
|
| Function |
Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modulate KCNU1 gating properties. {ECO:0000269|PubMed:22547800, ECO:0000269|PubMed:23129643}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Expression at the cell surface may require the presence of KCNU1.
|
| Tissue Specificity |
Mainly expressed in testis and skeletal muscle. {ECO:0000269|PubMed:22547800}.
|
![Western Blot: LRRC52 Overexpression Lysate (Adult Normal) [NBP2-08880] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for LRRC52.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/15649_LRRC52%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-08880-img0001.jpg)