Gene Symbol | LRRC52 |
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Entrez Gene | 440699 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 52 |
Other Description | BK channel auxiliary gamma subunit LRRC52|BK channel auxilliary gamma subunit LRRC52|leucine-rich repeat-containing protein 52 |
Swissprots | A2RUN7 Q8N7C0 Q5T9K5 |
Accessions | Q8N7C0 AA725678 AK098677 BAC05375 BC132981 AAI32982 BC132983 AAI32984 NM_001005214 NP_001005214 |
Function | Auxiliary protein of the large-conductance, voltage and calcium-activated potassium channel (BK alpha). Modulates gating properties by producing a marked shift in the BK channel's voltage dependence of activation in the hyperpolarizing direction, and in the absence of calcium. KCNU1 channel auxiliary protein. May modulate KCNU1 gating properties. {ECO:0000269|PubMed:22547800, ECO:0000269|PubMed:23129643}. |
Subcellular Location | Cell membrane {ECO:0000250}; Single-pass membrane protein {ECO:0000250}. Note=Expression at the cell surface may require the presence of KCNU1. |
Tissue Specificity | Mainly expressed in testis and skeletal muscle. {ECO:0000269|PubMed:22547800}. |
LRRC52 CRISPR/Cas9 KO Plasmid (h) - sc-406058 from Santa Cruz Biotechnology
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LRRC52 HDR Plasmid (h) - sc-406058-HDR from Santa Cruz Biotechnology
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LRRC52 Double Nickase Plasmid (h) - sc-406058-NIC from Santa Cruz Biotechnology
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LRRC52 Double Nickase Plasmid (h2) - sc-406058-NIC-2 from Santa Cruz Biotechnology
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LRRC52 CRISPR Activation Plasmid (h) - sc-406058-ACT from Santa Cruz Biotechnology
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LRRC52 CRISPR Activation Plasmid (h2) - sc-406058-ACT-2 from Santa Cruz Biotechnology
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LRRC52 Lentiviral Activation Particles (h) - sc-406058-LAC from Santa Cruz Biotechnology
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LRRC52 Lentiviral Activation Particles (h2) - sc-406058-LAC-2 from Santa Cruz Biotechnology
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LRRC52 siRNA (h) - sc-78591 from Santa Cruz Biotechnology
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LRRC52 shRNA Plasmid (h) - sc-78591-SH from Santa Cruz Biotechnology
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LRRC52 shRNA (h) Lentiviral Particles - sc-78591-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU025901 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN12751 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND12751 from Sigma-Aldrich
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LRRC52 siRNA (Human) - CRJ8263 from Cohesion Biosciences
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shRNA set against Human LRRC52 (NM_001005214.3) - SHH334675 from Creative biogene
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Human LRRC52 siRNA - orb278764 from Biorbyt
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LRRC52 shRNA Plasmid (Human) - CHJ8263 from Cohesion Biosciences
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LRRC52 miRNA 3'UTR clone - MiUTR4H-TG05189 from Creative biogene
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