CHST7

Gene Symbol CHST7
Entrez Gene 56548
Alt Symbol C6ST-2, GST-5
Species Human
Gene Type protein-coding
Description carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 7
Other Description N-acetylglucosamine 6-O-sulfotransferase 4|carbohydrate sulfotransferase 7|chondroitin 6-sulfotransferase-2|galactose/N-acetylglucosamine/N-acetylglucosamine 6-O-sulfotransferase 5|glcNAc6ST-4|gn6st-4
Swissprots O75667 Q9NS84
Accessions CCQ43621 EAW59267 EAW59268 Q9NS84 AB037187 BAB03217 AB040711 BAB13770 BC023971 BC045537 AAH45537 BP250418 BQ940898 DA155923 DA277492 GQ129386 ACT64520 GQ129387 ACT64521 NM_019886 NP_063939
Function Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the transfer of sulfate to position 6 of non-reducing N-acetylglucosamine (GlcNAc) residues. Preferentially acts on mannose-linked GlcNAc. Also able to catalyze the transfer of sulfate to position 6 of the N- acetylgalactosamine (GalNAc) residue of chondroitin. Also acts on core 2 mucin-type oligosaccharide and N-acetyllactosamine oligomer with a lower efficiency. Has weak or no activity toward keratan sulfate and oligosaccharides containing the Galbeta1-4GlcNAc. Catalyzes 6-O-sulfation of beta-benzyl GlcNAc but not alpha- or beta-benzyl GalNAc. {ECO:0000269|PubMed:10781596, ECO:0000269|PubMed:10913333, ECO:0000269|PubMed:10956661}.
Subcellular Location Golgi apparatus membrane {ECO:0000250}; Single-pass type II membrane protein {ECO:0000250}.
Tissue Specificity Widely expressed. Highly expressed in heart, spleen, liver and ovary. Expressed at lower level in brain, placenta, thyroid, spinal cord and peripheral blood leukocytes. Not expressed in adult skin. {ECO:0000269|PubMed:10781596, ECO:0000269|PubMed:10913333, ECO:0000269|PubMed:10956661}.
Top Pathways Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate

CHST7 CRISPR/Cas9 KO Plasmid (h) - sc-412708 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 HDR Plasmid (h) - sc-412708-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 Double Nickase Plasmid (h) - sc-412708-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 Double Nickase Plasmid (h2) - sc-412708-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 CRISPR Activation Plasmid (h) - sc-412708-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 CRISPR Activation Plasmid (h2) - sc-412708-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 Lentiviral Activation Particles (h) - sc-412708-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 Lentiviral Activation Particles (h2) - sc-412708-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

CHST7 siRNA (h) - sc-62120 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHST7 shRNA Plasmid (h) - sc-62120-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CHST7 shRNA (h) Lentiviral Particles - sc-62120-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN6115 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CHST7 siRNA (Human) - CRJ1148 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHST7 - MBS8211942 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human CHST7 (NM_019886.2) - SHH263841 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human CHST7(NM_019886.2) - SHG178041 from Creative biogene

Category siRNA
Species Reactivities Human

Human CHST7 siRNA - orb271649 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

CHST7 shRNA Plasmid (Human) - CHJ1148 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

CHST7 miRNA 3'UTR clone - MiUTR1H-02152 from Creative biogene

Species Reactivities Human
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