Gene Symbol | CNGA2 |
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Entrez Gene | 1260 |
Alt Symbol | CNCA, CNCA1, CNG2, OCNC1, OCNCALPHA, OCNCa |
Species | Human |
Gene Type | protein-coding |
Description | cyclic nucleotide gated channel alpha 2 |
Other Description | CNG channel alpha-2|CNG-2|cyclic nucleotide-gated cation channel 2|cyclic nucleotide-gated channel alpha-2|cyclic nucleotide-gated olfactory channel|cyclic-nucleotide-gated cation channel 2|cyclic-nucleotide-gated olfactory channel |
Swissprots | A0AVD0 Q16280 |
Accessions | AAD14207 EAW99409 Q16280 AK128186 BAG54645 BC126302 AAI26303 BC126304 AAI26305 NM_005140 NP_005131 |
Function | Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons. |
Subcellular Location | Membrane; Multi-pass membrane protein. |
Top Pathways | cAMP signaling pathway |
CNG-2 CRISPR/Cas9 KO Plasmid (h) - sc-410733 from Santa Cruz Biotechnology
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CNG-2 HDR Plasmid (h) - sc-410733-HDR from Santa Cruz Biotechnology
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CNG-2 Double Nickase Plasmid (h) - sc-410733-NIC from Santa Cruz Biotechnology
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CNG-2 Double Nickase Plasmid (h2) - sc-410733-NIC-2 from Santa Cruz Biotechnology
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CNG-2 CRISPR Activation Plasmid (h) - sc-410733-ACT from Santa Cruz Biotechnology
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CNG-2 CRISPR Activation Plasmid (h2) - sc-410733-ACT-2 from Santa Cruz Biotechnology
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CNG-2 Lentiviral Activation Particles (h) - sc-410733-LAC from Santa Cruz Biotechnology
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CNG-2 Lentiviral Activation Particles (h2) - sc-410733-LAC-2 from Santa Cruz Biotechnology
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CNG-2 siRNA (h) - sc-42393 from Santa Cruz Biotechnology
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CNG-2 shRNA Plasmid (h) - sc-42393-SH from Santa Cruz Biotechnology
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CNG-2 shRNA (h) Lentiviral Particles - sc-42393-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN2267 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2267 from Sigma-Aldrich
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CNGA2 siRNA (Human) - CRH0880 from Cohesion Biosciences
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CNGA2 RNAi - H00001260-R01 from Novus Biologicals
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CNGA2 - MBS8207686 from MyBioSource
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shRNA set against Human Cnga2 (NM_005140.1) - SHH266165 from Creative biogene
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shRNA set against Human CNGA2(NM_005140.1) - SHG186497 from Creative biogene
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Human CNGA2 siRNA - orb261382 from Biorbyt
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CNGA2 shRNA Plasmid (Human) - CHH0880 from Cohesion Biosciences
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CNGA2 miRNA 3'UTR clone - MiUTR1H-02265 from Creative biogene
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