CNGA2

Gene Symbol CNGA2
Entrez Gene 1260
Alt Symbol CNCA, CNCA1, CNG2, OCNC1, OCNCALPHA, OCNCa
Species Human
Gene Type protein-coding
Description cyclic nucleotide gated channel alpha 2
Other Description CNG channel alpha-2|CNG-2|cyclic nucleotide-gated cation channel 2|cyclic nucleotide-gated channel alpha-2|cyclic nucleotide-gated olfactory channel|cyclic-nucleotide-gated cation channel 2|cyclic-nucleotide-gated olfactory channel
Swissprots A0AVD0 Q16280
Accessions AAD14207 EAW99409 Q16280 AK128186 BAG54645 BC126302 AAI26303 BC126304 AAI26305 NM_005140 NP_005131
Function Odorant signal transduction is probably mediated by a G- protein coupled cascade using cAMP as second messenger. The olfactory channel can be shown to be activated by cyclic nucleotides which leads to a depolarization of olfactory sensory neurons.
Subcellular Location Membrane; Multi-pass membrane protein.
Top Pathways cAMP signaling pathway

CNG-2 (H-94) - sc-367212 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

CNG-2 (N-15) - sc-13701 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-CNGA2 antibody - ab79261 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab79261 stained HepG2 cells.  The cells were 4% formaldehyde fixed (10 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab79261 at 1/1000 dilution overnight at +4°C. The secondary antibody (green) was DyLight® 488 Goat anti-Rabbit IgG (H+L) (ab96899) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-CNGA2 Antibody (N-Terminus) - LS-C14506 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (N-Terminus) - LS-C14505 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa189-218, AP) - LS-C234010 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa189-218, APC) - LS-C234011 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa189-218, FITC) - LS-C234012 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa189-218, PE) - LS-C234014 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa189-218, Biotin) - LS-C234013 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa81-111, APC) - LS-C234016 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa391-440) - LS-C119881 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence of A549 cells, using CNGA2 Antibody. The picture on the right is treated with the synthesized peptide.

Anti-CNGA2 Antibody (aa81-111, Biotin) - LS-C234015 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa81-111, FITC) - LS-C234017 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa189-218, Azide-free, HRP) - LS-C249709 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa81-111, AP) - LS-C249133 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa81-111, PE) - LS-C234019 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa81-111, Azide-free, HRP) - LS-C249710 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa442-487) - LS-C313718 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa189-218) - LS-C320476 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa81-111) - LS-C320479 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CNGA2 Antibody (aa81-111) - LS-C168874 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Western blot of CNGA2 Antibody in K562 cell line lysates (35 ug/lane). CNGA2 (arrow) was detected using the purified antibody.

Anti-CNGA2 Antibody (aa412-664) - LS-C186270 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded SG xenograft using CNGA2 antibody at 1:500 dilution.

Anti-CNGA2 Antibody (aa189-218) IHC-plus™ - LS-B9623 from LifeSpan Bioscience

Prices $395.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
Anti-CNGA2 antibody IHC staining of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B9623 dilution 1:100.

CNGA2 Antibody - NBP1-85527 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CNGA2 Antibody [NBP1-85527] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG sp. Lane 4: Human plasma (IgG/HSA depleted). Lane 5: Human liver tissue. Lane 6: Human tonsil tissue
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