| Gene Symbol | CLCNKB |
|---|---|
| Entrez Gene | 1188 |
| Alt Symbol | CLCKB, ClC-K2, ClC-Kb |
| Species | Human |
| Gene Type | protein-coding |
| Description | chloride channel, voltage-sensitive Kb |
| Other Description | chloride channel protein ClC-Kb|chloride channel, kidney, B |
| Swissprots | Q5T5Q8 B3KUY3 P51801 Q5T5Q7 |
| Accessions | AAB65149 EAW51764 EAW51765 EAW51766 P51801 AK098217 BAG53595 AK292335 BAF85024 BC020873 AAH20873 BC033806 BC109243 DA369686 DA424588 DA623867 DA624942 DA627682 DA628551 DA633177 S80315 AAB35898 Z30644 CAA83121 XM_011540619 XP_011538921 XM_011540620 XP_011538922 XM_011540621 XP_011538923 NM_000085 NP_000076 NM_001165945 NP_001159417 |
| Function | Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms. {ECO:0000269|PubMed:11734858}. |
| Subcellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Specificity | Expressed predominantly in the kidney. {ECO:0000269|PubMed:11734858}. |
| Top Pathways | Collecting duct acid secretion |