| Gene Symbol |
CLCNKB
|
| Entrez Gene |
1188
|
| Alt Symbol |
CLCKB, ClC-K2, ClC-Kb
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
chloride channel, voltage-sensitive Kb
|
| Other Description |
chloride channel protein ClC-Kb|chloride channel, kidney, B
|
| Swissprots |
Q5T5Q8 B3KUY3 P51801 Q5T5Q7
|
| Accessions |
AAB65149 EAW51764 EAW51765 EAW51766 P51801 AK098217 BAG53595 AK292335 BAF85024 BC020873 AAH20873 BC033806 BC109243 DA369686 DA424588 DA623867 DA624942 DA627682 DA628551 DA633177 S80315 AAB35898 Z30644 CAA83121 XM_011540619 XP_011538921 XM_011540620 XP_011538922 XM_011540621 XP_011538923 NM_000085 NP_000076 NM_001165945 NP_001159417
|
| Function |
Voltage-gated chloride channel. Chloride channels have several functions including the regulation of cell volume; membrane potential stabilization, signal transduction and transepithelial transport. May be important in urinary concentrating mechanisms. {ECO:0000269|PubMed:11734858}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Expressed predominantly in the kidney. {ECO:0000269|PubMed:11734858}.
|
| Top Pathways |
Collecting duct acid secretion
|