HILPDA

Gene Symbol HILPDA
Entrez Gene 29923
Alt Symbol C7orf68, HIG-2, HIG2
Species Human
Gene Type protein-coding
Description hypoxia inducible lipid droplet-associated
Other Description hypoxia inducible gene 2|hypoxia-inducible gene 2 protein|hypoxia-inducible lipid droplet-associated protein|hypoxia-inducible protein 2
Swissprots Q9Y5L2 Q53HJ7 Q52LY5 A4D0Z5
Accessions CAI70370 CCD35269 CCQ77689 CCQ77698 CCQ77707 CCQ77716 CDH48195 CDH61617 CDH61671 CDH61690 CDH88988 CDH92526 CDH92540 CDH92551 CDH92798 CDH92895 CDI44670 CDI44679 EAL24309 EAW83654 EAW83655 EAW83656 Q9Y5L2 AF144755 AAD37585 AK024729 AK222583 BAD96303 AL691669 BC001863 AAH01863 BC008573 BC093742 AAH93742 BC112183 AAI12184 CD686848 CX784347 NM_001098786 NP_001092256 NM_013332 NP_037464
Function Increases intracellular lipid accumulation. Stimulates expression of cytokines including IL6, MIF and VEGFA. Enhances cell growth and proliferation. {ECO:0000269|PubMed:15930302, ECO:0000269|PubMed:20624928}.
Subcellular Location Lipid droplet. Secreted. Membrane {ECO:0000305}; Single-pass membrane protein {ECO:0000305}.
Tissue Specificity Highly expressed in renal cell carcinoma cells but barely detectable in adjacent normal kidney tissue. Detected in some cervical and endometrial cancers. Expression also detected in fetal kidney with little or no expression observed in normal adult heart, liver, lung, pancreas, prostate or spinal cord (at protein level). {ECO:0000269|PubMed:15930302, ECO:0000269|PubMed:20624928, ECO:0000269|PubMed:21614900}.

HIG2 (G-2) - sc-376704 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
HIG2 (G-2): sc-376704. Western blot analysis of HIG2 expression in non-transfected: sc-117752 (A) and mouse HIG2 transfected: sc-120779 (B) 293T whole cell lysates.

HIG2 (E-12) - sc-137519 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
HIG2 (E-12): sc-137519. Western blot analysis of HIG2 expression in non-transfected: sc-117752 (A) and mouse HIG2 transfected: sc-120779 (B) 293T whole cell lysates.

HIG2 (C-14) - sc-137518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
HIG2 (C-14): sc-137518. Western blot analysis of HIG2 expression in non-transfected: sc-117752 (A) and mouse HIG2 transfected: sc-120779 (B) 293T whole cell lysates.

Anti-HIG2 antibody - ab78349 from Abcam

Prices $242.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of HIG2 staining in human kidney_RCC formalin fixed paraffin embedded tissue section, performed on a Leica BondTM system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab78349, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-HILPDA / HIG2 Antibody (C-Terminus) - LS-C144423 from LifeSpan Bioscience

Prices $325.00, $890.00
Sizes 100 µg, 500 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of HIG2 in 3T3 cell lysate with HIG2 antibody at 1 ug/ml in (A) the absence and (B) the presence of blocking peptide.

HIG2 Antibody - NBP1-93960 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: HIG2 Antibody [NBP1-93960] - Staining of human cell line A549 shows localization to nucleoplasm & lipid droplets.

HIG2 Polyclonal Antibody - bs-15488R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HILPDA antibody produced in rabbit - HPA010515 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-AC010655.7: <B>Cat. No. HPA010515</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human colon shows cytoplasmic positivity in glandular cells.

HIG2 antibody - GTX16280 from GeneTex

Prices $329.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-HIG2 antibody used in Western blot. GTX16280

HIG2 antibody - orb75664 from Biorbyt

Prices $723.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of 3T3 cell lysate at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide using HIG2 antibody

Rabbit Anti-HIG2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-15488R-A350 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-15488R-A555 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-15488R-A647 from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, Cy3 Conjugated - bs-15488R-Cy3 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, Cy5 Conjugated - bs-15488R-Cy5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, Cy5.5 Conjugated - bs-15488R-Cy5.5 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, Cy7 Conjugated - bs-15488R-Cy7 from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, FITC Conjugated - bs-15488R-FITC from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, Biotin Conjugated - bs-15488R-Biotin from Bioss

Prices $325.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Rabbit Anti-HIG2 Polyclonal Antibody, HRP Conjugated - bs-15488R-HRP from Bioss

Prices $345.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HIG2 (C-term) antibody - AP55589PU-N from Acris Antibodies

Prices $340.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of HIG2 in 3T3 cell lysate with HIG2 antibody at 1 ug/mL in (A) the absence and (B) the presence of blocking peptide.

HIG2 Antibody - 6491 from ProSci

Prices $79.00, $325.00
Sizes 20 µg, 100 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of HIG2 in A549 cell lysate with HIG2 antibody at 1 μg/mL.

C7orf68 antibody - 15587-1-AP from Proteintech Group

Host Rabbit
Clonality Polyclonal

C7orf68, Polyclonal Antibody - MBS2519686 from MyBioSource

Prices $195.00, $270.00, $435.00
Sizes 60 µl, 120 µl, 200 µl
Host Rabbit
Clonality Polyclonal
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