Gene Symbol | SLC8A1 |
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Entrez Gene | 6546 |
Alt Symbol | NCX1 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 8 (sodium/calcium exchanger), member 1 |
Other Description | Na(+)/Ca(2+)-exchange protein 1|Na+/Ca++ exchanger|Na+/Ca2+ exchanger|sodium/calcium exchanger 1|solute carrier family 8 member 1 |
Swissprots | Q9UDN1 P32418 Q59GN4 D6W595 Q9UBL8 Q9UDN2 Q4QQG6 Q9UD55 Q9UKX6 A8K6N1 Q587I6 O95849 |
Accessions | AAF19235 AAF19237 AAX81985 EAX00331 EAX00332 EAX00333 EAX00334 EAX00335 EAX00336 P32418 AB209075 BAD92312 AF108388 AAF08987 AF108389 AAF08988 AF115505 AAD17213 AF128524 AAD26362 AK095013 AK125406 AK291696 BAF84385 BC098285 AAH98285 BC098308 AAH98308 BC098345 BC156359 AAI56360 BC172488 AAI72488 BX537482 CAD97765 BX648299 M91368 AAA35702 M96368 X91221 X91815 CAA62923 Y12878 CAA73378 Y12885 CAA73386 Y13032 CAA73477 Y13033 CAA73478 XM_005264514 XP_005264571 XM_006712081 XP_006712144 XM_006712082 XP_006712145 XM_006712083 XP_006712146 XM_006712084 XP_006712147 XM_006712085 XP_006712148 XM_006712086 XP_006712149 XM_011533048 XP_011531350 XM_011533049 XP_011531351 XM_011533050 XP_011531352 XM_011533051 XP_011531353 XM_011533052 XP_011531354 XM_011533053 XP_011531355 XM_011533054 XP_011531356 XM_011533055 XP_011531357 XM_011533056 XP_011531358 XM_011533057 XP_011531359 XM_011533058 XP_011531360 XM_011533059 XP_011531361 NM_001112800 NP_001106271 NM_001112801 NP_001106272 NM_001112802 NP_001106273 NM_001252624 NP_001239553 NM_021097 NP_066920 |
Function | Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores. {ECO:0000269|PubMed:1476165}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung. {ECO:0000269|PubMed:1476165}. |
Top Pathways | cGMP-PKG signaling pathway, Calcium signaling pathway, Adrenergic signaling in cardiomyocytes, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption |
SLC8A1 / NCX1 Antibody Blocking Peptide - LS-E9863 from LifeSpan Bioscience
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SLC8A1-Antibody-Center-Blocking-Peptide - BP8939c from Abgent, a WuXi AppTec company
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NCX1 Blocking Peptide - abx063271 from Abbexa
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NCX1 Blocking Peptide - CBP2077 from Cohesion Biosciences
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SLC8A1 Peptide - BS5816P from Bioworld Technology
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NCX1 Peptide - abx165049 from Abbexa
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SLC8A1 Peptide, Human - M34GP14653H from Creative Peptides
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Sodium Calcium Exchanger 1/NCX1 Recombinant Protein Antigen - NBP2-56483PEP from Novus Biologicals
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Sodium/calcium exchanger 1 (SLC8A1), Recombinant Protein - MBS950535 from MyBioSource
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Human SLC8A1 protein - orb419107 from Biorbyt
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SLC8A1 peptide - orb217940 from Biorbyt
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Recombinant Human SLC8A1 Protein (396-627 aa), His-tagged - SLC8A1-2278H from Creative Biomart
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