SLC8A1

Gene Symbol SLC8A1
Entrez Gene 6546
Alt Symbol NCX1
Species Human
Gene Type protein-coding
Description solute carrier family 8 (sodium/calcium exchanger), member 1
Other Description Na(+)/Ca(2+)-exchange protein 1|Na+/Ca++ exchanger|Na+/Ca2+ exchanger|sodium/calcium exchanger 1|solute carrier family 8 member 1
Swissprots Q9UDN1 P32418 Q59GN4 D6W595 Q9UBL8 Q9UDN2 Q4QQG6 Q9UD55 Q9UKX6 A8K6N1 Q587I6 O95849
Accessions AAF19235 AAF19237 AAX81985 EAX00331 EAX00332 EAX00333 EAX00334 EAX00335 EAX00336 P32418 AB209075 BAD92312 AF108388 AAF08987 AF108389 AAF08988 AF115505 AAD17213 AF128524 AAD26362 AK095013 AK125406 AK291696 BAF84385 BC098285 AAH98285 BC098308 AAH98308 BC098345 BC156359 AAI56360 BC172488 AAI72488 BX537482 CAD97765 BX648299 M91368 AAA35702 M96368 X91221 X91815 CAA62923 Y12878 CAA73378 Y12885 CAA73386 Y13032 CAA73477 Y13033 CAA73478 XM_005264514 XP_005264571 XM_006712081 XP_006712144 XM_006712082 XP_006712145 XM_006712083 XP_006712146 XM_006712084 XP_006712147 XM_006712085 XP_006712148 XM_006712086 XP_006712149 XM_011533048 XP_011531350 XM_011533049 XP_011531351 XM_011533050 XP_011531352 XM_011533051 XP_011531353 XM_011533052 XP_011531354 XM_011533053 XP_011531355 XM_011533054 XP_011531356 XM_011533055 XP_011531357 XM_011533056 XP_011531358 XM_011533057 XP_011531359 XM_011533058 XP_011531360 XM_011533059 XP_011531361 NM_001112800 NP_001106271 NM_001112801 NP_001106272 NM_001112802 NP_001106273 NM_001252624 NP_001239553 NM_021097 NP_066920
Function Rapidly transports Ca(2+) during excitation-contraction coupling. Ca(2+) is extruded from the cell during relaxation so as to prevent overloading of intracellular stores. {ECO:0000269|PubMed:1476165}.
Subcellular Location Cell membrane; Multi-pass membrane protein.
Tissue Specificity Expressed in cardiac sarcolemma, brain, kidney, liver, pancreas, skeletal muscle, placenta and lung. {ECO:0000269|PubMed:1476165}.
Top Pathways cGMP-PKG signaling pathway, Calcium signaling pathway, Adrenergic signaling in cardiomyocytes, Endocrine and other factor-regulated calcium reabsorption, Mineral absorption

NCX (H-300) - sc-32881 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
NCX (H-300): sc-32881. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing cytoplasmic staining of glandular cells.

NCX1 (C-15) - sc-30306 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-NCX1 antibody - ab135735 from Abcam

Prices $384.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-NCX1 antibody (ab135735) at 1/100 dilutionLane 1 : HL60 cell line lysateLane 2 : K562 cell line lysateLysates/proteins at 35 µg per lane.

Anti-NCX1 antibody [C2C12] - ab2869 from Abcam

Prices $403.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone C2C12
Immunocytochemistry/Immunofluorescence analysis of NCX1 shows staining in A2058 cells. NCX1 staining (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were incubated without (control) or with ab2869 (1:100) overnight at 4°C, washed with PBS and incubated with a DyLight-488 conjugated goat anti-mouse secondary antibody. Images were taken at 60X magnification.

Anti-NCX1 antibody [EPR12739] - ab177952 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12739
All lanes : Anti-NCX1 antibody [EPR12739] (ab177952) at 1/1000 dilutionLane 1 : Human fetal heart lysateLane 2 : Human fetal kidney lysateLane 3 : K562 lysateLysates/proteins at 10 µg per lane.SecondaryGoat anti-rabbit HRP at 1/2000 dilution

Anti-SLC8A1 / NCX1 Antibody (N-Terminus) - LS-C16739 from LifeSpan Bioscience

Prices $560.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (clone C2C12) - LS-C84111 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone C2C12

Anti-SLC8A1 / NCX1 Antibody (aa371-525) - LS-C73201 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal

Anti-SLC8A1 / NCX1 Antibody (clone R3F1) - LS-C85329 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone R3F1

Anti-SLC8A1 / NCX1 Antibody - LS-C86181 from LifeSpan Bioscience

Prices $665.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Internal, APC) - LS-C279995 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Internal, AP) - LS-C279996 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Internal, Biotin) - LS-C279997 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Internal, FITC) - LS-C280000 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Internal, Azide-free, HRP) - LS-C280001 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Internal, PE) - LS-C280002 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (aa336-381) - LS-C313847 from LifeSpan Bioscience

Prices $345.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Internal) - LS-C328007 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (aa46-95) - LS-C201462 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human ACHN. SLC8A1 antibody dilution 1.0 ug/ml.

Anti-SLC8A1 / NCX1 Antibody (aa296-325) - LS-C161275 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
SLC8A1 Antibody IHC of formalin-fixed and paraffin-embedded mouse brain followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-SLC8A1 / NCX1 Antibody - LS-C16734 from LifeSpan Bioscience

Prices $375.00
Sizes 50 µl
Host Mouse
Clonality Monoclonal

Anti-SLC8A1 / NCX1 Antibody (Cytoplasmic Domain) - LS-C16735 from LifeSpan Bioscience

Prices $495.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Anti-SLC8A1 / NCX1 Antibody (Cytoplasmic Domain) - LS-C16737 from LifeSpan Bioscience

Prices $385.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal

Sodium Calcium Exchanger 1/NCX1 Antibody (6H2) - NB300-127 from Novus Biologicals

Prices $309.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6H2
Western Blot: NCX1 Antibody (6H2) [NB300-127] - Western blot of various tissues showing specific immunolabeling of the ~120k and ~160k NaCX-1 protein. Lane 1 - Brain; Lane 2 - Heart; Lane 3 - Kidney; Lane 4 - Lung; Lane 5 - Spleen.

Rabbit Anti-NCX1/SLC8A1 Polyclonal Antibody - bs-1550R from Bioss

Host Rabbit
Clonality Polyclonal
Lane 1: mouse kidney lysates Lane 2: mouse liver lysates probed with Anti NCX1/SLC8A1 Polyclonal Antibody, Unconjugated (bs-1550R) at 1:200 in 4˚C. Followed by conjugation to secondary antibody (bs-0295G-HRP) at 1:3000 90min in 37˚C. Predicted band 106kD. Observed band size: 106kD.
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