RNF185

Gene Symbol RNF185
Entrez Gene 91445
Alt Symbol -
Species Human
Gene Type protein-coding
Description ring finger protein 185
Other Description BSK65-MONO1|BSK65-MONO2|BSK65-PANC1|BSK65-PANC2|BSK65-TEST1|BSK65-TEST2|BSK65-TEST3|E3 ubiquitin-protein ligase RNF185
Swissprots A8K5C1 Q96GF1 Q8N900 A9X3T8
Accessions CAH05436 CAH05489 EAW59943 EAW59944 EAW59945 EAW59946 EAW59947 EAW59948 EAW59949 EAW59950 EAW59951 EAW59952 EAW59953 Q96GF1 AA258379 AK027035 AK075154 AK095947 BAC04659 AK291236 BAF83925 AK297414 BAG59848 BC009504 AAH09504 BC012817 AAH12817 BC017302 BC026040 AAH26040 BC033166 AAH33166 BC035684 AAH35684 BX648019 CR456349 CAG30235 CU013059 CAK54490 CU013347 CAK54789 DA498404 DB134817 DQ296559 ABB97506 DQ296560 ABB97507 DQ296561 ABB97508 DQ296562 ABB97509 DQ296563 ABB97510 DQ296564 ABB97511 DQ296565 ABB97512 XM_006724373 XP_006724436 XM_006724374 XP_006724437 NM_001135824 NM_001135825 NP_001129297 NM_152267 NP_689480 NR_024209 NR_024210 NR_024211 NR_024212
Function E3 ubiquitin-protein ligase that regulates selective mitochondrial autophagy by mediating 'Lys-63'-linked polyubiquitination of BNIP1. Responsible for the cotranslational ubiquitination and degradation of CFTR in the ERAD pathway. Preferentially associates with the E2 enzymes UBE2J1 and UBE2J2. {ECO:0000269|PubMed:21931693, ECO:0000269|PubMed:24019521}.
Subcellular Location Mitochondrion outer membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein.
Top Pathways Protein processing in endoplasmic reticulum

RNF185 (P-12) - sc-86830 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
RNF185 (P-12): sc-86830. Western blot analysis of RNF185 expression in HeLa whole cell lysate.

RNF185 (N-12) - sc-86829 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

Anti-RNF185 antibody - ab107333 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RNF185 antibody (ab107333) at 1/500 dilution + K562 cell line lysates at 35 µg

Anti-RNF185 antibody - ab80461 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-RNF185 antibody (ab80461) at 1 µg/ml + Human fetal liver lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-RNF185 antibody - ab73118 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-RNF185 antibody (ab73118) at 1/500 dilutionLane 1 : RNF185 transfected 293T cell lysateLane 2 : non transfected lysateLysates/proteins at 25 µg per lane.Secondarygoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-RNF185 antibody [EPR14070] - ab181227 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14070
All lanes : Anti-RNF185 antibody [EPR14070] (ab181227) at 1/10000 dilutionLane 1 : HeLa cell lysateLane 2 : 293 cell lysateLane 3 : K562 cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-RNF185 antibody [EPR14070-94] - ab181999 from Abcam

Prices $357.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR14070-94
Western blot analysis of immunoprecipitation pellet from HeLa cell lysate immunoprecipitated using ab181999 at 1/40 dilution (lane 1) or a negative control (lane 2) followed by Anti-Rabbit IgG (HRP), specific to the non-reduced form of IgG at 1/1500 dilution.

Anti-RNF185 Antibody (aa88-117, APC) - LS-C273214 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF185 Antibody (aa91-121) - LS-C324701 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF185 Antibody (aa74-123) - LS-C80571 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Fetal liver lysate. Antibody concentration: 1.0 ug/ml. Gel concentration: 12%.

Anti-RNF185 Antibody (aa88-117) - LS-C162636 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RN185 Antibody western blot of mouse kidney tissue and K562 cell line lysates (35 ug/lane). The RN185 antibody detected the RN185 protein (arrow).

Anti-RNF185 Antibody (aa88-117, AP) - LS-C268328 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF185 Antibody (aa88-117, Biotin) - LS-C268329 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF185 Antibody (aa88-117, FITC) - LS-C268330 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF185 Antibody (aa88-117, Azide-free, HRP) - LS-C268331 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RNF185 Antibody (aa88-117, PE) - LS-C268332 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

RNF185 Antibody - NBP1-59761 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal

RNF185 Antibody - NBP2-13241 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: RNF185 Antibody [NBP2-13241] - Staining of human stomach, upper shows strong cytoplasmic positivity in glandular cells.

RNF185 Antibody - H00091445-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: RNF185 Antibody [H00091445-B01P] - Analysis of RNF185 expression in transfected 293T cell line by RNF185 polyclonal antibody. Lane 1: RNF185 transfected lysate(21.12 KDa). Lane 2: Non-transfected lysate.

RNF185 Antibody - H00091445-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: RNF185 Antibody [H00091445-B01] - analysis of RNF185 expression in transfected 293T cell line by RNF185 MaxPab polyclonal antibody (B01). Lane 1: RNF185 transfected lysate (20.50 KDa). Lane 2: Non-transfected lysate.

RNF185 Polyclonal Antibody - bs-9261R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ANTI-RN185 (CENTER) antibody produced in rabbit - SAB1306102 from Sigma-Aldrich

Prices $326.00
Sizes 40 tst
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RN185 (Center): <B>Cat. No. SAB1306102</B>: RN185 Antibody (Center) western blot analysis in CHO cell line lysates (35 μg/lane).

Anti-RNF185 antibody produced in mouse - SAB1401941 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-RNF185, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401941</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~21.12 kDa using RNF185 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-RNF185 antibody produced in rabbit - SAB2102024 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-RNF185: <B>Cat. No.SAB2102024</B>: RNF185 in Fetal Liver tissue lysate with RNF185 antibody at 1.0 μg/mL.

Anti-RNF185 antibody produced in rabbit - HPA048329 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RNF185:<B>Cat. No. HPA048329</B>: Immunohistochemical staining of human stomach, upper shows strong cytoplasmic positivity in glandular cells.
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