| Gene Symbol |
TMPRSS9
|
| Entrez Gene |
360200
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
transmembrane protease, serine 9
|
| Other Description |
polyserase 1|polyserase-1|polyserase-I|polyserine protease 1|transmembrane protease serine 9|transmembrane serine protease 9
|
| Swissprots |
Q6ZND6 Q7Z411 Q7Z410
|
| Accessions |
EAW69382 Q7Z410 AB109390 BAF02295 AJ488946 CAD35758 AJ488947 CAD35759 AK131261 BAD18439 BC140386 AAI40387 XM_011527978 XP_011526280 XM_011527979 XP_011526281 XM_011527980 XP_011526282 XM_011527981 XP_011526283 XM_011527982 XP_011526284 XM_011527983 XP_011526285 NM_182973 NP_892018
|
| Function |
Serase-1 and serase-2 are serine proteases that hydrolyze the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln- Gly-Arg-AMC. In contrast, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Ala- Pro-Ala-AMC are not significantly hydrolyzed.
|
| Subcellular Location |
Cell membrane {ECO:0000269|PubMed:12886014}; Single-pass type II membrane protein {ECO:0000269|PubMed:12886014}.
|
| Tissue Specificity |
Expressed in fetal human tissues, such as kidney, liver, lung and brain, and in a variety of tumor cell lines. Weakly expressed in adult tissues including skeletal muscle, liver, placenta and heart. {ECO:0000269|PubMed:12886014}.
|