Gene Symbol | TMPRSS9 |
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Entrez Gene | 360200 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | transmembrane protease, serine 9 |
Other Description | polyserase 1|polyserase-1|polyserase-I|polyserine protease 1|transmembrane protease serine 9|transmembrane serine protease 9 |
Swissprots | Q6ZND6 Q7Z411 Q7Z410 |
Accessions | EAW69382 Q7Z410 AB109390 BAF02295 AJ488946 CAD35758 AJ488947 CAD35759 AK131261 BAD18439 BC140386 AAI40387 XM_011527978 XP_011526280 XM_011527979 XP_011526281 XM_011527980 XP_011526282 XM_011527981 XP_011526283 XM_011527982 XP_011526284 XM_011527983 XP_011526285 NM_182973 NP_892018 |
Function | Serase-1 and serase-2 are serine proteases that hydrolyze the peptides N-t-Boc-Gln-Ala-Arg-AMC and N-t-Boc-Gln- Gly-Arg-AMC. In contrast, N-t-Boc-Ala-Phe-Lys-AMC and N-t-Boc-Ala- Pro-Ala-AMC are not significantly hydrolyzed. |
Subcellular Location | Cell membrane {ECO:0000269|PubMed:12886014}; Single-pass type II membrane protein {ECO:0000269|PubMed:12886014}. |
Tissue Specificity | Expressed in fetal human tissues, such as kidney, liver, lung and brain, and in a variety of tumor cell lines. Weakly expressed in adult tissues including skeletal muscle, liver, placenta and heart. {ECO:0000269|PubMed:12886014}. |
Polyserase-1 CRISPR/Cas9 KO Plasmid (h) - sc-415677 from Santa Cruz Biotechnology
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Polyserase-1 HDR Plasmid (h) - sc-415677-HDR from Santa Cruz Biotechnology
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Polyserase-1 Double Nickase Plasmid (h) - sc-415677-NIC from Santa Cruz Biotechnology
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Polyserase-1 Double Nickase Plasmid (h2) - sc-415677-NIC-2 from Santa Cruz Biotechnology
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Polyserase-1 CRISPR Activation Plasmid (h) - sc-415677-ACT from Santa Cruz Biotechnology
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Polyserase-1 CRISPR Activation Plasmid (h2) - sc-415677-ACT-2 from Santa Cruz Biotechnology
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Polyserase-1 Lentiviral Activation Particles (h) - sc-415677-LAC from Santa Cruz Biotechnology
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Polyserase-1 Lentiviral Activation Particles (h2) - sc-415677-LAC-2 from Santa Cruz Biotechnology
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Polyserase-1 siRNA (h) - sc-76195 from Santa Cruz Biotechnology
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Polyserase-1 shRNA Plasmid (h) - sc-76195-SH from Santa Cruz Biotechnology
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Polyserase-1 shRNA (h) Lentiviral Particles - sc-76195-V from Santa Cruz Biotechnology
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CompoZr® Knockout ZFN Kit - CKOZFN21713 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21713 from Sigma-Aldrich
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TMPRSS9 siRNA (Human) - CRJ7602 from Cohesion Biosciences
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TMPRSS9 - MBS8211103 from MyBioSource
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shRNA set against Human TMPRSS9 (NM_182973.1) - SHH431540 from Creative biogene
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shRNA set against Human TMPRSS9(NM_182973.1) - SHL083214 from Creative biogene
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Human TMPRSS9 siRNA - orb278103 from Biorbyt
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TMPRSS9 shRNA Plasmid (Human) - CHJ7602 from Cohesion Biosciences
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TMPRSS9 miRNA 3'UTR clone - MiUTR1H-10580 from Creative biogene
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