VPS29

Gene Symbol VPS29
Entrez Gene 51699
Alt Symbol DC15, DC7, PEP11
Species Human
Gene Type protein-coding
Description vacuolar protein sorting 29 homolog (S. cerevisiae)
Other Description PEP11 homolog|hVPS29|retromer protein|vacuolar protein sorting-associated protein 29|vacuolar sorting protein VPS29/PEP11|vesicle protein sorting 29|x 007 protein
Swissprots Q6IAH3 Q9NRP1 Q9H0W0 Q6FIF8 Q9UBQ0 Q9NRU7 Q502Y5
Accessions EAW97918 EAW97919 Q9UBQ0 AA148059 AB578890 AB578891 AB578892 AB618733 BAJ83889 AF086379 AF168716 AAF87318 AF175264 AAF89952 AF193795 AAF04596 AF201936 AAF86872 AF201946 AAF17238 AK000499 AK129767 AK130510 AL136614 CAB66549 AL832866 CAI46196 AM392835 CAL37713 BC000880 AAH00880 BC015095 AAH15095 BC017964 BC032462 AAH32462 BC095446 AAH95446 BF030144 BG707325 BM806646 BU568689 CB158821 CR457182 CAG33463 CR533468 CAG38499 XM_006719459 XP_006719522 XM_006719460 XP_006719523 XM_011538484 XP_011536786 XM_011538485 XP_011536787 NM_001282150 NP_001269079 NM_001282151 NP_001269080 NM_016226 NP_057310 NM_057180 NP_476528 NR_104099 NR_104100 NR_104101 NR_104102
Function Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins. The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5. Required to regulate transcytosis of the polymeric immunoglobulin receptor (pI
Subcellular Location Cytoplasm. Membrane; Peripheral membrane protein. Endosome membrane {ECO:0000250|UniProtKB:Q9QZ88}; Peripheral membrane protein {ECO:0000250|UniProtKB:Q9QZ88}. Early endosome {ECO:0000305}. Late endosome {ECO:0000305}.
Tissue Specificity Ubiquitous. Highly expressed in heart, lung, placenta, spleen, peripheral blood leukocytes, thymus, colon skeletal muscle, kidney and brain.

VPS29 (D-1) - sc-398874 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VPS29 (D-1): sc-398874. Western blot analysis of VPS29 expression in WI-38 (A), JAR (B), ACHN (C) and Hep G2 (D) whole cell lysates and human spleen tissue extract (E).

VPS29 (H-182) - sc-98611 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

VPS29 (N-15) - sc-69121 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-VPS29 antibody - ab76330 from Abcam

Prices $370.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-VPS29 antibody - ab98929 from Abcam

Prices $376.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-VPS29 antibody (ab98929) at 1 µg/ml + ACHN cell lysate at 10 µg

Anti-VPS29 antibody - ab10160 from Abcam

Prices $378.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Anti-VPS29 antibody (ab10160) at 0.1 µg/ml + Human Spleen lysate (RIPA buffer, 35µg total protein per lane)

Anti-VPS29 antibody - ab51972 from Abcam

Prices $376.00
Sizes 200 µl
Host Goat
Clonality Polyclonal
ab51972 at 3.8 µg/ml staining VPS29 in Human uterus tissue. Steamed antigen retrieval with citrate buffer pH 6 was performed. Antibody detected by AP-staining.

Anti-VPS29 Antibody (C-Terminus) - LS-C95260 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-VPS29 Antibody (aa35-84) - LS-C108024 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
VPS29 antibody LS-C108024 Western blot of ACHN lysate.

Anti-VPS29 Antibody (aa174-186) - LS-C55674 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (0.1 ug/ml) of Human Spleen lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-VPS29 Antibody (aa40-54) IHC-plus™ - LS-B3946 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-VPS29 antibody IHC of human uterus. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B3946 concentration 3.75 ug/ml.

VPS29 Antibody - NB100-1387 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Western Blot: VPS29 Antibody [NB100-1387] - Western Blot analysis of VPS29 in Human Spleen lysate (RIPA buffer, 35ug total protein per lane) using NB100-1387 (0.1ug/ml). Primary incubated for 1 hour using chemiluminescence.

VPS29 Antibody - NBP2-20871 from Novus Biologicals

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: VPS29 Antibody [NBP2-20871] - Sample (30 ug of whole cell lysate) A: HepG2 12% SDS PAGE gel, diluted at 1:2000.

VPS29 Antibody - NB100-41109 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Immunohistochemistry-Paraffin: VPS29 Antibody [NB100-41109] - (3.8ug/ml) staining of paraffin embedded Human Uterus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

VPS29 Antibody - NBP1-30994 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: VPS29 Antibody [NBP1-30994] - Sample(30 ug of whole cell lysate)A:293T 12% SDS PAGE, antibody diluted at 1:1500.

VPS29 Antibody - H00051699-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

Anti-VPS29 antibody produced in goat - SAB2501545 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-VPS29 antibody produced in rabbit - HPA039748 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-VPS29: <B>Cat. No. HPA039748</B>: Immunohistochemical staining of human lateral ventricle shows strong cytoplasmic positivity in neuronal cells.

Anti-VPS29, C-Terminal antibody produced in goat - SAB2501105 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-VPS29 (C Terminus): <B>Cat. No. SAB2501105</B>: staining (0.1 μg/mL) of Human Spleen lysate (RIPA buffer, 35 μg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

Anti-VPS29, (N-terminal) antibody produced in rabbit - SAB2106012 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-VPS29 (N-Terminal): <B>Cat. No. SAB2106012</B>: VPS29 in ACHN cell lysates with VPS29 antibody at 1.0 μg/mL.

VPS29 antibody - N-terminal region (ARP56858_P050) - ARP56858_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

VPS29-C-Terminus-Antibody - AF2152a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2152a staining (0.1 µg/ml) of Human Spleen lysate (RIPA buffer, 35 µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.

VPS29-Internal-Antibody-internal-region - AF2528a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF2528a (3.8 µg/ml) staining of paraffin embedded Human Uterus. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

VPS29 Antibody (OAEB00843) - OAEB00843 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

VPS29 antibody - C-terminal region (OAEB01281) - OAEB01281 from Aviva Systems Biology

Prices $289.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
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