| Gene Symbol |
RGS1
|
| Entrez Gene |
5996
|
| Alt Symbol |
1R20, BL34, HEL-S-87, IER1, IR20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
regulator of G-protein signaling 1
|
| Other Description |
B-cell activation protein BL34|early response protein 1R20|epididymis secretory protein Li 87|immediate-early response 1, B-cell specific|regulator of G-protein signalling 1
|
| Swissprots |
B2RDM9 Q9H1W2 Q08116 Q07918 B4DZY0
|
| Accessions |
EAW91226 EAW91227 EAW91228 Q08116 AA962409 AF493925 AAM12639 AK093544 AK303138 BAG64242 AK315607 BAG37976 AL039059 BC015510 AAH15510 BG536972 BT006668 AAP35314 BU783195 DQ890651 ABM81577 DQ893831 ABM84757 EU668340 ACF94493 X73427 CAA51826 NM_002922 NP_002913
|
| Function |
Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation.
|
| Tissue Specificity |
B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high.
|
