Gene Symbol | RGS1 |
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Entrez Gene | 5996 |
Alt Symbol | 1R20, BL34, HEL-S-87, IER1, IR20 |
Species | Human |
Gene Type | protein-coding |
Description | regulator of G-protein signaling 1 |
Other Description | B-cell activation protein BL34|early response protein 1R20|epididymis secretory protein Li 87|immediate-early response 1, B-cell specific|regulator of G-protein signalling 1 |
Swissprots | B2RDM9 Q9H1W2 Q08116 Q07918 B4DZY0 |
Accessions | EAW91226 EAW91227 EAW91228 Q08116 AA962409 AF493925 AAM12639 AK093544 AK303138 BAG64242 AK315607 BAG37976 AL039059 BC015510 AAH15510 BG536972 BT006668 AAP35314 BU783195 DQ890651 ABM81577 DQ893831 ABM84757 EU668340 ACF94493 X73427 CAA51826 NM_002922 NP_002913 |
Function | Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. This protein may be involved in the regulation of B-cell activation and proliferation. |
Tissue Specificity | B-cell specific. Expression is relatively low in B-cells and chronic lymphocytic leukemia B-cells; however, in other types of malignant B-cell such as non-Hodgkin lymphoma and hairy cell leukemia, expression is constitutively high. |
RGS1 CRISPR/Cas9 KO Plasmid (h) - sc-404874 from Santa Cruz Biotechnology
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RGS1 HDR Plasmid (h) - sc-404874-HDR from Santa Cruz Biotechnology
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RGS1 Double Nickase Plasmid (h) - sc-404874-NIC from Santa Cruz Biotechnology
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RGS1 Double Nickase Plasmid (h2) - sc-404874-NIC-2 from Santa Cruz Biotechnology
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RGS1 CRISPR Activation Plasmid (h) - sc-404874-ACT from Santa Cruz Biotechnology
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RGS1 CRISPR Activation Plasmid (h2) - sc-404874-ACT-2 from Santa Cruz Biotechnology
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RGS1 Lentiviral Activation Particles (h) - sc-404874-LAC from Santa Cruz Biotechnology
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RGS1 Lentiviral Activation Particles (h2) - sc-404874-LAC-2 from Santa Cruz Biotechnology
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RGS1 siRNA (h) - sc-36408 from Santa Cruz Biotechnology
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RGS1 shRNA Plasmid (h) - sc-36408-SH from Santa Cruz Biotechnology
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RGS1 shRNA (h) Lentiviral Particles - sc-36408-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU039951 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18214 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18214 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06334 from Sigma-Aldrich
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RGS1 siRNA (Human) - CRH4064 from Cohesion Biosciences
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RGS1 - MBS8218995 from MyBioSource
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shRNA set against Human RGS1 (NM_002922.3) - SHH394808 from Creative biogene
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shRNA set against Human RGS1(NM_002922.3) - SHR178608 from Creative biogene
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RGS1 shRNA Plasmid (Human) - CHH4064 from Cohesion Biosciences
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RGS1 miRNA 3'UTR clone - MiUTR1H-08777 from Creative biogene
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