| Gene Symbol |
GET4
|
| Entrez Gene |
51608
|
| Alt Symbol |
C7orf20, CEE, CGI-20, TRC35
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
golgi to ER traffic protein 4 homolog (S. cerevisiae)
|
| Other Description |
Golgi to ER traffic protein 4 homolog|H_NH1244M04.5|conserved edge expressed protein|conserved edge protein|conserved edge-expressed protein|transmembrane domain recognition complex 35 kDa subunit|transmembrane domain recognition complex, 35kDa
|
| Swissprots |
A4D2Q1 Q7L5D6 B3KNC7 Q9Y309 Q9UFC9
|
| Accessions |
EAL23708 EAW87179 EAW87180 Q7L5D6 AF132954 AAD27729 AK023560 AK024305 BAG51289 AK097899 BAG53546 AK124149 AK125863 BAG54258 AL133014 CAB61355 BC003550 AAH03550 BG109419 BM843540 BM980767 NM_015949 NP_057033
|
| Function |
Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting. {ECO:0000269|PubMed:20676083}.
|
| Subcellular Location |
Cytoplasm, cytosol {ECO:0000269|PubMed:20676083}.
|
![Western Blot: GET4 Overexpression Lysate (Adult Normal) [NBL1-08544] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for GET4.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9330_GET4%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-08544-img0002.jpg)