Gene Symbol | GET4 |
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Entrez Gene | 51608 |
Alt Symbol | C7orf20, CEE, CGI-20, TRC35 |
Species | Human |
Gene Type | protein-coding |
Description | golgi to ER traffic protein 4 homolog (S. cerevisiae) |
Other Description | Golgi to ER traffic protein 4 homolog|H_NH1244M04.5|conserved edge expressed protein|conserved edge protein|conserved edge-expressed protein|transmembrane domain recognition complex 35 kDa subunit|transmembrane domain recognition complex, 35kDa |
Swissprots | A4D2Q1 Q7L5D6 B3KNC7 Q9Y309 Q9UFC9 |
Accessions | EAL23708 EAW87179 EAW87180 Q7L5D6 AF132954 AAD27729 AK023560 AK024305 BAG51289 AK097899 BAG53546 AK124149 AK125863 BAG54258 AL133014 CAB61355 BC003550 AAH03550 BG109419 BM843540 BM980767 NM_015949 NP_057033 |
Function | Component of the BAT3 complex, a multiprotein complex involved in the post-translational delivery of tail-anchored (TA) membrane proteins to the endoplasmic reticulum membrane. TA membrane proteins, also named type II transmembrane proteins, contain a single C-terminal transmembrane region. The complex acts by facilitating TA proteins capture by ASNA1/TRC40: it is recruited to ribosomes synthesizing membrane proteins, interacts with the transmembrane region of newly released TA proteins, and transfers them to ASNA1/TRC40 for targeting. {ECO:0000269|PubMed:20676083}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:20676083}. |
Get4 CRISPR/Cas9 KO Plasmid (h) - sc-407595 from Santa Cruz Biotechnology
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Get4 HDR Plasmid (h) - sc-407595-HDR from Santa Cruz Biotechnology
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Get4 Double Nickase Plasmid (h) - sc-407595-NIC from Santa Cruz Biotechnology
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Get4 Double Nickase Plasmid (h2) - sc-407595-NIC-2 from Santa Cruz Biotechnology
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Get4 CRISPR Activation Plasmid (h) - sc-407595-ACT from Santa Cruz Biotechnology
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Get4 CRISPR Activation Plasmid (h2) - sc-407595-ACT-2 from Santa Cruz Biotechnology
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Get4 Lentiviral Activation Particles (h) - sc-407595-LAC from Santa Cruz Biotechnology
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Get4 Lentiviral Activation Particles (h2) - sc-407595-LAC-2 from Santa Cruz Biotechnology
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Get4 siRNA (h) - sc-89392 from Santa Cruz Biotechnology
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Get4 shRNA Plasmid (h) - sc-89392-SH from Santa Cruz Biotechnology
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Get4 shRNA (h) Lentiviral Particles - sc-89392-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU140351 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9236 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9236 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07916 from Sigma-Aldrich
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GET4 siRNA (Human) - CRH9858 from Cohesion Biosciences
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GET4 - MBS827179 from MyBioSource
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shRNA set against Human GET4 (NM_015949.2) - SHH300534 from Creative biogene
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shRNA set against Human C7orf20(NM_015949.2) - SHG128201 from Creative biogene
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GET4 shRNA Plasmid (Human) - CHH9858 from Cohesion Biosciences
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GET4 miRNA 3'UTR clone - MiUTR1H-01481 from Creative biogene
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