Gene Symbol | CHRM1 |
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Entrez Gene | 1128 |
Alt Symbol | HM1, M1, M1R |
Species | Human |
Gene Type | protein-coding |
Description | cholinergic receptor, muscarinic 1 |
Other Description | acetylcholine receptor, muscarinic 1|muscarinic acetylcholine receptor M1 |
Swissprots | Q96RH1 P11229 |
Accessions | CAA33334 CAA36291 CAA68560 EAW74124 EAW74125 EAW74126 P11229 AF385587 AAK68112 AF498915 AAM18938 AJ006520 CAA07081 AK312374 BAG35292 BC007740 AAH07740 BC022984 AAH22984 BT007166 AAP35830 DQ890725 ABM81651 DQ892720 ABM83646 DQ895969 ABM86895 XM_011544742 XP_011543044 NM_000738 NP_000729 |
Function | The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is Pi turnover. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. |
Top Pathways | Calcium signaling pathway, PI3K-Akt signaling pathway, cAMP signaling pathway, Regulation of actin cytoskeleton, Neuroactive ligand-receptor interaction |
mAChR M1 (G-9) - sc-365966 from Santa Cruz Biotechnology
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mAChR M1 (H-120) - sc-9106 from Santa Cruz Biotechnology
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mAChR M1 (H-2) - sc-365548 from Santa Cruz Biotechnology
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mAChR M1 (C-20) - sc-7470 from Santa Cruz Biotechnology
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mAChR M1 (N-19) - sc-7471 from Santa Cruz Biotechnology
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Anti-muscarinic Acetylcholine Receptor 1 antibody - ab75178 from Abcam
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Anti-muscarinic Acetylcholine Receptor 1 antibody - ab77098 from Abcam
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Anti-Muscarinic Acetylcholine Receptor 1 antibody - Cytoplasmic domain - ab180636 from Abcam
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Anti-CHRM1 / M1 Antibody (aa451-460) - LS-C9130 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (C-Terminus) - LS-C37392 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (C-Terminus) - LS-C37391 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (C-Terminus) - LS-C130850 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody - LS-C285478 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (aa210-363, Biotin) - LS-C299137 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (aa210-363, FITC) - LS-C302026 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (aa326-375) - LS-C151419 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (Biotin) - LS-C317277 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (FITC) - LS-C318854 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (HRP) - LS-C317278 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody - LS-C192735 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (aa210-363) - LS-C293321 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (aa295-344) - LS-C120626 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (Arg336) - LS-C177149 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (C-Terminus) - LS-C54654 from LifeSpan Bioscience
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Anti-CHRM1 / M1 Antibody (aa303-317) - LS-C313301 from LifeSpan Bioscience
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