Gene Symbol | LAMP1 |
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Entrez Gene | 3916 |
Alt Symbol | CD107a, LAMPA, LGP120 |
Species | Human |
Gene Type | protein-coding |
Description | lysosomal-associated membrane protein 1 |
Other Description | CD107 antigen-like family member A|LAMP-1|lysosome-associated membrane glycoprotein 1|lysosome-associated membrane protein 1 |
Swissprots | Q8WU33 B4DWL3 Q96I40 Q9NP13 P11279 Q9BRD2 |
Accessions | EAX09202 EAX09203 P11279 AB209319 BAD92556 AK092398 BAG52545 AK301584 BAG63075 BC006345 AAH06345 BC007845 AAH07845 BC021288 AAH21288 BC025335 BC093044 AAH93044 BU849686 DB462451 DQ892614 ABM83540 DQ895854 ABM86780 J03263 AAA59524 J04182 AAA60382 XM_011537494 XP_011535796 XM_011537495 XP_011535797 NM_005561 NP_005552 |
Function | Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane. Colocalizes with OSBPL1A at the late endosome. |
Top Pathways | Lysosome, Phagosome, Tuberculosis |
LAMP-1 CRISPR/Cas9 KO Plasmid (h) - sc-400120 from Santa Cruz Biotechnology
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LAMP-1 HDR Plasmid (h) - sc-400120-HDR from Santa Cruz Biotechnology
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LAMP-1 Double Nickase Plasmid (h) - sc-400120-NIC from Santa Cruz Biotechnology
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LAMP-1 Double Nickase Plasmid (h2) - sc-400120-NIC-2 from Santa Cruz Biotechnology
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LAMP-1 CRISPR Activation Plasmid (h) - sc-400120-ACT from Santa Cruz Biotechnology
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LAMP-1 CRISPR Activation Plasmid (h2) - sc-400120-ACT-2 from Santa Cruz Biotechnology
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LAMP-1 Lentiviral Activation Particles (h) - sc-400120-LAC from Santa Cruz Biotechnology
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LAMP-1 Lentiviral Activation Particles (h2) - sc-400120-LAC-2 from Santa Cruz Biotechnology
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LAMP-1 siRNA (h) - sc-29389 from Santa Cruz Biotechnology
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LAMP-1 shRNA Plasmid (h) - sc-29389-SH from Santa Cruz Biotechnology
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LAMP-1 shRNA (h) Lentiviral Particles - sc-29389-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU028781 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN11539 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND11539 from Sigma-Aldrich
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LAMP1 siRNA (Human) - CRH2655 from Cohesion Biosciences
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shRNA set against Human LAMP1 (NM_005561.3) - SHH328335 from Creative biogene
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shRNA set against Human LAMP1(NM_005561.3) - SHH141761 from Creative biogene
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LAMP-1 CRISPR/Cas9 KO Plasmid (h2) - sc-400120-KO-2 from Santa Cruz Biotechnology
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LAMP-1 HDR Plasmid (h2) - sc-400120-HDR-2 from Santa Cruz Biotechnology
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Human LAMP1 siRNA - orb263157 from Biorbyt
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LAMP1 shRNA Plasmid (Human) - CHH2655 from Cohesion Biosciences
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LAMP1 miRNA 3'UTR clone - MiUTR1H-05567 from Creative biogene
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