LAMP1

Gene Symbol LAMP1
Entrez Gene 3916
Alt Symbol CD107a, LAMPA, LGP120
Species Human
Gene Type protein-coding
Description lysosomal-associated membrane protein 1
Other Description CD107 antigen-like family member A|LAMP-1|lysosome-associated membrane glycoprotein 1|lysosome-associated membrane protein 1
Swissprots Q8WU33 B4DWL3 Q96I40 Q9NP13 P11279 Q9BRD2
Accessions EAX09202 EAX09203 P11279 AB209319 BAD92556 AK092398 BAG52545 AK301584 BAG63075 BC006345 AAH06345 BC007845 AAH07845 BC021288 AAH21288 BC025335 BC093044 AAH93044 BU849686 DB462451 DQ892614 ABM83540 DQ895854 ABM86780 J03263 AAA59524 J04182 AAA60382 XM_011537494 XP_011535796 XM_011537495 XP_011535797 NM_005561 NP_005552
Function Presents carbohydrate ligands to selectins. Also implicated in tumor cell metastasis.
Subcellular Location Cell membrane; Single-pass type I membrane protein. Endosome membrane; Single-pass type I membrane protein. Lysosome membrane; Single-pass type I membrane protein. Late endosome. Note=This protein shuttles between lysosomes, endosomes, and the plasma membrane. Colocalizes with OSBPL1A at the late endosome.
Top Pathways Lysosome, Phagosome, Tuberculosis

LAMP1 (D2D11) XP ® Rabbit mAb - 9091 from Cell Signaling Technology

Prices $109.00, $277.00
Sizes 20 µl (2 western blots), 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2D11
Western blot analysis of extracts from various cell lines using LAMP1 (D2D11) XP ® Rabbit mAb.

LAMP1 (C54H11) Rabbit mAb - 3243 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone C54H11
Western blot analysis of extracts from HeLa, Neuro2a and COS cells using LAMP1 (C54H11) Antibody.

LAMP-1 (C-20) - sc-8098 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LAMP-1 (C-20): sc-8098. Immunofluorescence staining of methanol-fixed HeLa cells showing cytoplasmic localization.

LAMP-1 (E-5) - sc-17768 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LAMP-1 (E-5): sc-17768. Western blot analysis of LAMP-1 expression in HeLa (A) JAR (B) and ECV304 (C) whole cell lysates.

LAMP-1 (H-228) - sc-5570 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
LAMP-1 (H-228): sc-5570. Western blot analysis of LAMP-1 expression in HeLa (A) and U-937 (B) whole cell lysates.

LAMP-1 (H4A3) - sc-20011 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LAMP-1 (H4A3) PE: sc-20011 PE. FCM analysis of JAR cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

LAMP-1 (H5G11) - sc-18821 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
LAMP-1 (H5G11) PE: sc-18821 PE. FCM analysis of JAR cells. Black line histogram represents the isotype control, normal mouse IgG<sub>1</sub>: sc-2866.

LAMP-1 (N-19) - sc-8099 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
LAMP-1 (N-19): sc-8099. Immunoperoxidase staining of formalin fixed, paraffin-embedded human breast tumor showing membrane and cytoplasmic localization.

Anti-LAMP1 antibody - ab62562 from Abcam

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Lane 1 : Anti-LAMP1 antibody (ab62562) at 1 µg/mlLane 2 : Anti-LAMP1 antibody (ab62562) at 2 µg/mlLane 1 : EL4 cell lysateLane 2 : EL4 cell lysateLysates/proteins at 15 µg per lane.

Anti-LAMP1 antibody - ab19294 from Abcam

Prices $392.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of LAMP1 staining in human lung formalin fixed paraffin embedded tissue section, performed on a Leica Bond system using the standard protocol F. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH6, epitope retrieval solution 1) for 20 mins. The section was then incubated with ab19294, 5µg/ml, for 15 mins at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-LAMP1 antibody - ab187185 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunofluorescent analysis of rat NRK cells (fixed and permeabilized with 4% paraformaldehyde followed by 0.4% Saponin) labeling LAMP1 with ab187185 at 10 μg/ml, followed by Goat anti rabbit IgG (FITC conjugate) secondary antibody.

Anti-LAMP1 antibody [1D4B] - ab25245 from Abcam

Prices $401.00
Sizes 100 µg
Host Rat
Clonality Monoclonal
Clone 1D4B
ab25245 staining mouse macrophage, hepatoma cell by ICC/IF.  Cells were PFA fixed and permeabilized in Triton X-100 prior to blocking in 1% BSA for 30 minutes at 25°C.  The primary antibody was diluted 1/1000 and incubated with the sample for 16 hours at 4°C.  An Alexa Fluor® 594 conjugated goat anti-mouse antibody was used as the secondary.See Abreview

Anti-LAMP1 antibody [B-T47] - ab47208 from Abcam

Prices $370.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone B-T47

Anti-LAMP1 antibody [B-T47] - ab47209 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone B-T47

Anti-LAMP1 antibody [B-T47] (Phycoerythrin) - ab47210 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone B-T47

Anti-LAMP1 antibody (Cy3 ®) - ab67283 from Abcam

Prices $372.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-LAMP1 antibody [EPR4204] - ab108597 from Abcam

Prices $390.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4204
All lanes : Anti-LAMP1 antibody [EPR4204] (ab108597) at 1/1000 dilutionLane 1 : HeLa cell lysateLane 2 : JAR cell lysateLane 3 : Jurkat cell lysateLane 4 : A431 cell lysateLysates/proteins at 10 µg per lane.

Anti-LAMP1 antibody [H4A3] - ab25630 from Abcam

Prices $400.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone H4A3
Overlay histogram showing Jurkat cells stained with ab25630 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab25630, 1/20 dilution) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG1 [ICIGG1] (ab91353, 2µg/1x106 cells) used under the same conditions. Acquisition of >5,000 events was performed. This antibody gave a positive signal in Jurkat cells fixed with methanol (5 min)/permeabilized in 0.1% PBS-Tween used under the same conditions.

Anti-LAMP1 antibody [H4A3] - ab119127 from Abcam

Prices $378.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone H4A3

Anti-LAMP1 antibody [H4A3] (Alexa Fluor® 488) - ab187591 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone H4A3

Anti-LAMP1 antibody [H4A3] (Biotin) - ab25446 from Abcam

Prices $370.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone H4A3

Anti-LAMP1 antibody [H4A3] (FITC) - ab25406 from Abcam

Prices $188.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone H4A3
Overlay histogram showing HT1080 cells stained with ab25406 (red line). The cells were fixed with 4% paraformaldehydel (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab25406, 0.5µg/1x106 cells) for 30 min at 22ºC. Isotype control antibody (black line) was mouse IgG1 (1µg/1x106 cells ). Acquisition of >5,000 events was performed. This antibody gave a positive signal in HT1080 cells fixed with 80% methano/permeabilized in 0.1% PBS-Tween used under the same conditions.

Anti-LAMP1 antibody [H4A3] (PE/Cy5®) - ab25222 from Abcam

Prices $185.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone H4A3

Anti-LAMP1 antibody [H4A3] (Phycoerythrin) - ab25367 from Abcam

Prices $370.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone H4A3

Anti-LAMP1 antibody [H4A3], prediluted (Allophycocyanin) - ab131601 from Abcam

Prices $186.00
Sizes 50 tests
Host Mouse
Clonality Monoclonal
Clone H4A3
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