NUDT4

Gene Symbol	NUDT4
Entrez Gene	11163
Alt Symbol	DIPP2, DIPP2alpha, DIPP2beta, HDCMB47P
Species	Human
Gene Type	protein-coding
Description	nudix (nucleoside diphosphate linked moiety X)-type motif 4
Other Description	DIPP-2|diadenosine 5',5'''-P1,P6-hexaphosphate hydrolase 2|diphosphoinositol polyphosphate phosphohydrolase 2|diphosphoinositol polyphosphate phosphohydrolase type 2
Swissprots	Q9NZK0 Q9NPC5 Q68DD7 Q9NZJ9 B7Z916 Q4AEJ6 Q9NZK1 Q53EZ2 Q9NS30
Accessions	EAW97475 EAW97476 EAW97477 EAW97478 EAW97479 Q9NZJ9 AB007956 BAE16985 AF067803 AAF75563 AF191649 AAF68855 AF191650 AAF68856 AF191651 AAF68857 AF191652 AAF68858 AF191653 AAF68859 AF191654 AF191655 AK223497 BAD97217 AK304296 BAH14152 AK315778 BAG38126 BC012069 AAH12069 BC051310 AAH51310 BG777287 BM193309 BP315657 BT020109 AAV38912 BT020110 AAV38913 CB961167 CN335956 CR749445 CAH18283 DC323957 DQ786307 DQ892199 ABM83125 DQ895394 ABM86320 XM_011537794 XP_011536096 XM_011537795 XP_011536097 XM_011537796 XP_011536098 NM_001301022 NP_001287951 NM_001301023 NP_001287952 NM_001301024 NP_001287953 NM_019094 NP_061967 NM_199040 NP_950241
Function	Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), PP-InsP4 and [PP]2-InsP4 (bisdiphosphoinositol tetrakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphate Ap6A, but not Ap5A. The major reaction products are ADP and p4a from Ap6A. Also able to hydrolyze 5-phosphoribose 1-diphosphate. Does not play a role in U8 snoRNA decapping activity. Binds U8 snoRNA. {ECO:0000269|PubMed:10777568}.
Subcellular Location	Cytoplasm {ECO:0000269|PubMed:12121577}.
Tissue Specificity	Expressed in heart and, at lower level in skeletal muscle, pancreas and kidney. {ECO:0000269|PubMed:10777568}.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human NUDT4 full length protein - ab161332 from Abcam Category Protein Source Wheat germ Species Human

Human NUDT4 full length protein - ab156348 from Abcam Category Protein Source E. coli Species Human

NUDT4 Antibody Blocking Peptide - LS-E4791 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NUDT4 Recombinant Protein - H00011163-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

Recombinant Human NUDT4 Protein - NBP2-23304 from Novus Biologicals Category Protein Prices $349.00 Sizes 50 µg Source E.coli Species Human

NUDT4-Antibody-N-term-Blocking-Peptide - BP17167a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

Human NUDT4 Enzyme - orb191440 from Biorbyt Category Protein Prices $170.00, $289.00 Sizes 2 μg, 10 μg Source Escherichia Coli. Species Human

NUDT4 protein (His tag) - 80R-2805 from Fitzgerald Category Protein Prices $365.00 Sizes 50 µg Source E.coli

NUDT4 / DIPP2 (1-180, His-tag) - AR50924PU-N from Acris Antibodies Category Protein Prices $1,010.00 Sizes 250 µg Source E. coli Species Human

NUDT4 / DIPP2 (1-180, His-tag) - AR50924PU-S from Acris Antibodies Category Protein Prices $410.00 Sizes 50 µg Source E. coli Species Human

NUDT4 / DIPP2 - H00011163-P01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NUDT4 / DIPP2 - H00011163-P01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NUDT4, 1-180aa, Human, His tag, E.coli - 01-P2100 from ARP American Research Products Category Protein Prices $179.00, $449.00, $1,089.00 Sizes 10 µg, 50 µg, 250 µg Species Human

Recombinant Human nudix (nucleoside diphosphate linked moiety X)-type motif 4, His-tagged - NUDT4-585H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human Diphosphoinositol polyphosphate phosphohydrolase 2(NUDT4) - CSB-YP865192HU CSB-EP865192HU CSB-BP865192HU CSB-MP865192HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NuDT4, 1-180aa, Human, His tag, E.coli - ATGP2100 from ATGen Category Protein Prices $105.00, $320.00, $960.00 Sizes 10 µg, 50 µg, 250 µg Species Human

NUDT4 / DIPP2 (transcript variant 1) - TP304100 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

NUDT4 Recombinant Protein Antigen - NBP1-84250PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

NUDT4 Peptide, Human - M34GP10717H from Creative Peptides Category Peptide Source Synthetic. Species Human

Nudix Type Motif 4, Human Recombinant - 228-20655-1 from RayBiotech Category Protein Prices $118.00 Sizes 1 µg Species Human

NuDT4 - PAT-82099-1 from Nordic BioSite Category Protein Species Human

NuDT4 - PAT-82099-2 from Nordic BioSite Category Protein Species Human

Diphosphoinositol polyphosphate phosphohydrolase 2 (NUDT4), Recombinant Protein - MBS1368501 from MyBioSource Category Protein Prices $925.00, $925.00, $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,835.00, $1,835.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Orangutan

Diphosphoinositol polyphosphate phosphohydrolase 2 (NUDT4), Recombinant Protein - MBS1352377 from MyBioSource Category Protein Prices $925.00, $925.00, $1,150.00, $1,150.00, $1,380.00, $1,380.00, $1,835.00, $1,835.00 Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell) Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

Nudix Type Motif 4, Recombinant Protein - MBS145555 from MyBioSource Category Protein Prices $140.00, $205.00, $5,015.00 Sizes 2 µg, 10 µg, 1 mg Source E Coli

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