RPGR

Gene Symbol RPGR
Entrez Gene 6103
Alt Symbol COD1, CORDX1, CRD, PCDX, RP15, RP3, XLRP3, orf15
Species Human
Gene Type protein-coding
Description retinitis pigmentosa GTPase regulator
Other Description X-linked retinitis pigmentosa GTPase regulator|retinitis pigmentosa 15|retinitis pigmentosa 3 GTPase regulator
Swissprots Q92834 O00702 Q8N5T6 Q93039 E9PE28 Q9UMR1 Q3KN84 B1ARN3 Q9HD29 O00737
Accessions AAG00550 AAG00551 CAC86116 EAW59441 EAW59442 EAW59443 EAW59444 Q92834 AJ238395 CAB54002 AK223491 BAD97211 AK291832 BAF84521 AY927527 BC031624 AAH31624 BK005711 DAA05713 BP233620 BX644678 CA313540 DQ426891 DQ980616 DQ980617 JF432801 ADZ16018 U57629 AAC50481 X97668 CAA66258 XM_005272633 XP_005272690 XM_011543940 XP_011542242 NM_000328 NP_000319 NM_001034853 NP_001030025 NM_001023582
Function Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia. {ECO:0000250, ECO:0000269|PubMed:21933838}.
Subcellular Location Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9R0X5}. Golgi apparatus {ECO:0000269|PubMed:15772089}.
Tissue Specificity Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments. {ECO:0000269|PubMed:12140192}.

RPGR (H-70) - sc-366626 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
RPGR (H-70): sc-366626. Western blot analysis of RPGR expression in Neuro-2A whole cell lysate (A) and mouse testis tissue extract (B).

RPGR (L-18) - sc-14672 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RPGR (L-18): sc-14672. Immunoperoxidase staining of formalin fixed, paraffin-embedded human liver tissue showing cytoplasmic and membrane staining of hepatocytes and hepatic sinusoid cells.

Anti-RPGR antibody - ab121143 from Abcam

Prices $443.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical staining of Human liver with ab121143 at 1/200 dilution.

Anti-RPGR antibody - C-terminal - ab170583 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of Formalin-fixed, Paraffin-embedded Human liver tissue labeling RPGR with ab170583 at 1/10 dilution followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-RPGR antibody - N-terminal - ab180729 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) analysis of mouse kidney tissue labelling RPGR with ab180729 at 1/100. Magnification: 200x.

Anti-RPGR Antibody (aa744-772, AP) - LS-C268479 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody (aa744-772, APC) - LS-C268480 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody (aa744-772, Biotin) - LS-C268481 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody (aa744-772, FITC) - LS-C268482 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody (aa744-772, Azide-free, HRP) - LS-C268483 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody (aa744-772, PE) - LS-C285100 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody (aa743-772) - LS-C324774 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody - LS-C341200 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-RPGR Antibody (aa744-772) - LS-C162691 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
RPGR Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human liver tissue followed by peroxidase-conjugated secondary antibody and DAB staining.

Anti-RPGR Antibody - LS-C331722 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry of paraffin-embedded mouse kidney using RPGR antibody at dilution of 1:100 (200x lens).

RPGR Antibody - NBP1-84412 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: RPGR Antibody [NBP1-84412] - Staining of human liver shows distinct cytoplasmic and membranous positivity in hepatocytes.

ANTI-RPGR (C-TERM) antibody produced in rabbit - SAB1303617 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>RPGR (C-term): <B>Cat. No. SAB1303617</B>: RPGR in Human liver tissue with RPGR antibody (C-term) at 10 μg/mL.

Anti-RPGR antibody produced in rabbit - HPA001593 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-RPGR: <B>Cat. No. HPA001593</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human kidney tissue showing strong cytoplasmic and/or membranous staining of cells in tubuli.

RPGR-Antibody-C-term - AP12226b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
RPGR Antibody (C-term) (Cat. #AP12226b) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the RPGR antibody detected the RPGR protein (arrow).

RPGR Antibody - C-terminal region (OAAB08472) - OAAB08472 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

RPGR Polyclonal Antibody - A1844 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using RPGR antibody.

RPGR antibody - orb136251 from Biorbyt

Prices $247.00, $374.00, $519.00
Sizes 50 μg, 100 μg, 200 μg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines using RPGR antibody

RPGR antibody - 70R-19955 from Fitzgerald

Prices $375.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal

RPGR Antibody - abx001524 from Abbexa

Host Rabbit
Clonality Polyclonal

RPGR Antibody - abx026667 from Abbexa

Host Rabbit
Clonality Polyclonal
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