Gene Symbol | RPGR |
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Entrez Gene | 6103 |
Alt Symbol | COD1, CORDX1, CRD, PCDX, RP15, RP3, XLRP3, orf15 |
Species | Human |
Gene Type | protein-coding |
Description | retinitis pigmentosa GTPase regulator |
Other Description | X-linked retinitis pigmentosa GTPase regulator|retinitis pigmentosa 15|retinitis pigmentosa 3 GTPase regulator |
Swissprots | Q92834 O00702 Q8N5T6 Q93039 E9PE28 Q9UMR1 Q3KN84 B1ARN3 Q9HD29 O00737 |
Accessions | AAG00550 AAG00551 CAC86116 EAW59441 EAW59442 EAW59443 EAW59444 Q92834 AJ238395 CAB54002 AK223491 BAD97211 AK291832 BAF84521 AY927527 BC031624 AAH31624 BK005711 DAA05713 BP233620 BX644678 CA313540 DQ426891 DQ980616 DQ980617 JF432801 ADZ16018 U57629 AAC50481 X97668 CAA66258 XM_005272633 XP_005272690 XM_011543940 XP_011542242 NM_000328 NP_000319 NM_001034853 NP_001030025 NM_001023582 |
Function | Could be a guanine-nucleotide releasing factor. Plays a role in ciliogenesis. Probably regulates cilia formation by regulating actin stress filaments and cell contractility. Plays an important role in photoreceptor integrity. May play a critical role in spermatogenesis and in intraflagellar transport processes (By similarity). May be involved in microtubule organization and regulation of transport in primary cilia. {ECO:0000250, ECO:0000269|PubMed:21933838}. |
Subcellular Location | Cytoplasm, cytoskeleton, flagellum axoneme {ECO:0000250|UniProtKB:Q9R0X5}. Golgi apparatus {ECO:0000269|PubMed:15772089}. |
Tissue Specificity | Heart, brain, placenta, lung, liver, muscle, kidney, retina, pancreas and fetal retinal pigment epithelium. Isoform 3 is found only in the retina. Colocalizes with RPGRIP1 in the outer segment of rod photoreceptors and cone outer segments. {ECO:0000269|PubMed:12140192}. |
RPGR (H-70) - sc-366626 from Santa Cruz Biotechnology
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RPGR (L-18) - sc-14672 from Santa Cruz Biotechnology
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Anti-RPGR antibody - ab121143 from Abcam
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Anti-RPGR antibody - C-terminal - ab170583 from Abcam
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Anti-RPGR antibody - N-terminal - ab180729 from Abcam
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Anti-RPGR Antibody (aa744-772, AP) - LS-C268479 from LifeSpan Bioscience
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Anti-RPGR Antibody (aa744-772, APC) - LS-C268480 from LifeSpan Bioscience
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Anti-RPGR Antibody (aa744-772, Biotin) - LS-C268481 from LifeSpan Bioscience
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Anti-RPGR Antibody (aa744-772, FITC) - LS-C268482 from LifeSpan Bioscience
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Anti-RPGR Antibody (aa744-772, Azide-free, HRP) - LS-C268483 from LifeSpan Bioscience
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Anti-RPGR Antibody (aa744-772, PE) - LS-C285100 from LifeSpan Bioscience
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Anti-RPGR Antibody (aa743-772) - LS-C324774 from LifeSpan Bioscience
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Anti-RPGR Antibody - LS-C341200 from LifeSpan Bioscience
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Anti-RPGR Antibody (aa744-772) - LS-C162691 from LifeSpan Bioscience
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Anti-RPGR Antibody - LS-C331722 from LifeSpan Bioscience
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RPGR Antibody - NBP1-84412 from Novus Biologicals
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ANTI-RPGR (C-TERM) antibody produced in rabbit - SAB1303617 from Sigma-Aldrich
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Anti-RPGR antibody produced in rabbit - HPA001593 from Sigma-Aldrich
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RPGR-Antibody-C-term - AP12226b from Abgent, a WuXi AppTec company
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RPGR Antibody - C-terminal region (OAAB08472) - OAAB08472 from Aviva Systems Biology
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RPGR Polyclonal Antibody - A1844 from ABclonal
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RPGR antibody - orb136251 from Biorbyt
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RPGR antibody - 70R-19955 from Fitzgerald
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RPGR Antibody - abx001524 from Abbexa
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RPGR Antibody - abx026667 from Abbexa
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