| Gene Symbol |
OPN4
|
| Entrez Gene |
94233
|
| Alt Symbol |
MOP
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
opsin 4
|
| Other Description |
melanopsin|opsin-4
|
| Swissprots |
Q8NGQ9 Q14D01 B7ZLB3 Q2PP22 Q9UHM6
|
| Accessions |
AAF24978 ABC40723 BAC05951 EAW80330 EAW80331 Q9UHM6 AK310520 BC029291 BC113558 AAI13559 BC143688 AAI43689 BM672338 CD634966 CD634974 DQ426884 NM_001030015 NP_001025186 NM_033282 NP_150598
|
| Function |
Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all- trans retinal back to 11-cis retinal (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Found in soma, dendrites and proximal part of axons of certain retinal ganglion cells. {ECO:0000250}.
|
| Tissue Specificity |
Eye. Expression is restricted within the ganglion and amacrine cell layers of the retina. {ECO:0000269|PubMed:10632589}.
|
![Western Blot: Melanopsin Overexpression Lysate (Adult Normal) [NBP2-05892] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for Melanopsin.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_1/17601_Melanopsin%2520Overexpression%2520Lysate%2520%2528Adult%2520Normal%2529-Western%2520Blot-NBP2-05892-img0001.jpg)