Gene Symbol | OPN4 |
---|---|
Entrez Gene | 94233 |
Alt Symbol | MOP |
Species | Human |
Gene Type | protein-coding |
Description | opsin 4 |
Other Description | melanopsin|opsin-4 |
Swissprots | Q8NGQ9 Q14D01 B7ZLB3 Q2PP22 Q9UHM6 |
Accessions | AAF24978 ABC40723 BAC05951 EAW80330 EAW80331 Q9UHM6 AK310520 BC029291 BC113558 AAI13559 BC143688 AAI43689 BM672338 CD634966 CD634974 DQ426884 NM_001030015 NP_001025186 NM_033282 NP_150598 |
Function | Photoreceptor required for regulation of circadian rhythm. Contributes to pupillar reflex and other non-image forming responses to light. May be able to isomerize covalently bound all- trans retinal back to 11-cis retinal (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Found in soma, dendrites and proximal part of axons of certain retinal ganglion cells. {ECO:0000250}. |
Tissue Specificity | Eye. Expression is restricted within the ganglion and amacrine cell layers of the retina. {ECO:0000269|PubMed:10632589}. |
melanopsin CRISPR/Cas9 KO Plasmid (h) - sc-402783 from Santa Cruz Biotechnology
|
||||||||
melanopsin HDR Plasmid (h) - sc-402783-HDR from Santa Cruz Biotechnology
|
||||||||
melanopsin Double Nickase Plasmid (h) - sc-402783-NIC from Santa Cruz Biotechnology
|
||||||||
melanopsin Double Nickase Plasmid (h2) - sc-402783-NIC-2 from Santa Cruz Biotechnology
|
||||||||
melanopsin CRISPR Activation Plasmid (h) - sc-402783-ACT from Santa Cruz Biotechnology
|
||||||||
melanopsin CRISPR Activation Plasmid (h2) - sc-402783-ACT-2 from Santa Cruz Biotechnology
|
||||||||
melanopsin Lentiviral Activation Particles (h) - sc-402783-LAC from Santa Cruz Biotechnology
|
||||||||
melanopsin Lentiviral Activation Particles (h2) - sc-402783-LAC-2 from Santa Cruz Biotechnology
|
||||||||
melanopsin siRNA (h) - sc-40146 from Santa Cruz Biotechnology
|
||||||||
melanopsin shRNA Plasmid (h) - sc-40146-SH from Santa Cruz Biotechnology
|
||||||||
melanopsin shRNA (h) Lentiviral Particles - sc-40146-V from Santa Cruz Biotechnology
|
||||||||
Melanopsin RNAi - H00094233-R04 from Novus Biologicals
|
||||||||
Melanopsin RNAi - H00094233-R03 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU157251 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN15742 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND15742 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR06251 from Sigma-Aldrich
|
||||||||
OPN4 siRNA (Human) - CRJ4259 from Cohesion Biosciences
|
||||||||
shRNA set against Human OPN4 (NM_033282.3) - SHH366684 from Creative biogene
|
||||||||
shRNA set against Human OPN4(NM_001030015.2) - SHR071196 from Creative biogene
|
||||||||
shRNA set against Human OPN4(NM_033282.3) - SHR071214 from Creative biogene
|
||||||||
Human OPN4 siRNA - orb274760 from Biorbyt
|
||||||||
OPN4 shRNA Plasmid (Human) - CHJ4259 from Cohesion Biosciences
|
||||||||
OPN4 miRNA 3'UTR clone - MiUTR1H-07069 from Creative biogene
|
||||||||
OPN4 miRNA 3'UTR clone - MiUTR1H-07070 from Creative biogene
|