Gene Symbol | TRIM39 |
---|---|
Entrez Gene | 56658 |
Alt Symbol | RNF23, TFP, TRIM39B |
Species | Human |
Gene Type | protein-coding |
Description | tripartite motif containing 39 |
Other Description | E3 ubiquitin-protein ligase TRIM39|ring finger protein 23|testis-abundant finger protein|tripartite motif-containing 39|tripartite motif-containing protein 39 |
Swissprots | Q96IB6 Q76BL3 Q9HCM9 Q5STG3 Q8IYT9 Q5STG4 |
Accessions | BAD13703 BAD13704 BAE78608 EAX03283 EAX03284 EAX03285 EAX03286 Q9HCM9 AB046381 BAB16374 AI159923 AK292512 BAF85201 AX776007 CAE11703 BC007661 AAH07661 BC034985 AAH34985 BT007370 AAP36034 DB071507 NM_021253 NP_067076 NM_172016 NP_742013 |
Function | E3 ubiquitin-protein ligase. May facilitate apoptosis by inhibiting APC/C-Cdh1-mediated poly-ubiquitination and subsequent proteasome-mediated degradation of the pro-apoptotic protein MOAP1. {ECO:0000269|PubMed:19100260, ECO:0000269|PubMed:22529100}. |
Subcellular Location | Cytoplasm, cytosol {ECO:0000269|PubMed:19100260}. Mitochondrion {ECO:0000269|PubMed:19100260}. Note=Found predominantly in the cytosol. Partial shift from the cytosol to the mitochondria when colocalized with MOAP1. |
Tissue Specificity | Ubiquitous; highly expressed in brain, heart, kidney, liver, skeletal muscle, spleen and testis. {ECO:0000269|PubMed:19100260}. |
RNF23 CRISPR/Cas9 KO Plasmid (h) - sc-409294 from Santa Cruz Biotechnology
|
||||||||
RNF23 HDR Plasmid (h) - sc-409294-HDR from Santa Cruz Biotechnology
|
||||||||
RNF23 Double Nickase Plasmid (h) - sc-409294-NIC from Santa Cruz Biotechnology
|
||||||||
RNF23 Double Nickase Plasmid (h2) - sc-409294-NIC-2 from Santa Cruz Biotechnology
|
||||||||
RNF23 CRISPR Activation Plasmid (h) - sc-409294-ACT from Santa Cruz Biotechnology
|
||||||||
RNF23 CRISPR Activation Plasmid (h2) - sc-409294-ACT-2 from Santa Cruz Biotechnology
|
||||||||
RNF23 Lentiviral Activation Particles (h) - sc-409294-LAC from Santa Cruz Biotechnology
|
||||||||
RNF23 Lentiviral Activation Particles (h2) - sc-409294-LAC-2 from Santa Cruz Biotechnology
|
||||||||
RNF23 siRNA (h) - sc-76420 from Santa Cruz Biotechnology
|
||||||||
RNF23 shRNA Plasmid (h) - sc-76420-SH from Santa Cruz Biotechnology
|
||||||||
RNF23 shRNA (h) Lentiviral Particles - sc-76420-V from Santa Cruz Biotechnology
|
||||||||
RNF23 RNAi - H00056658-R02 from Novus Biologicals
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN21977 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND21977 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR09298 from Sigma-Aldrich
|
||||||||
TRIM39 siRNA (Human) - CRJ1163 from Cohesion Biosciences
|
||||||||
RNF23 RNAi - H00056658-R01 from Novus Biologicals
|
||||||||
TRIM39 - MBS826866 from MyBioSource
|
||||||||
shRNA set against Human TRIM39 (NM_021253.3) - SHH434696 from Creative biogene
|
||||||||
Human TRIM39 siRNA - orb271664 from Biorbyt
|
||||||||
TRIM39 shRNA Plasmid (Human) - CHJ1163 from Cohesion Biosciences
|
||||||||
TRIM39 miRNA 3'UTR clone - MiUTR3H-07892 from Creative biogene
|
||||||||
TRIM39 miRNA 3'UTR clone - MiUTR3H-07893 from Creative biogene
|