| Gene Symbol |
VPS37B
|
| Entrez Gene |
79720
|
| Alt Symbol |
-
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
vacuolar protein sorting 37 homolog B (S. cerevisiae)
|
| Other Description |
ESCRT-I complex subunit VPS37B|hVps37B|vacuolar protein sorting 37B|vacuolar protein sorting-associated protein 37B
|
| Swissprots |
Q9H9H4
|
| Accessions |
EAW98348 EAW98349 EAW98350 EAW98351 Q9H9H4 AK022812 BAB14255 BC005882 AAH05882 BU629695 XM_005253622 XP_005253679 XM_006719602 XP_006719665 XM_011538742 XP_011537044 XM_011538743 XP_011537045 XM_011538744 XP_011537046 XM_011538745 XP_011537047 XM_011538746 XP_011537048 NM_024667 NP_078943
|
| Function |
Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation. {ECO:0000269|PubMed:15218037}.
|
| Subcellular Location |
Late endosome membrane {ECO:0000269|PubMed:15218037}; Peripheral membrane protein {ECO:0000269|PubMed:15218037}. Note=Recruited to the endosomal membrane in a VPS4A-dependent fashion.
|
| Tissue Specificity |
Widely expressed. Expressed in macrophages and lymphocytes. {ECO:0000269|PubMed:15218037}.
|
| Top Pathways |
Endocytosis
|
![Western Blot: VPS37B Overexpression Lysate (Adult Normal) [NBL1-17749] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for VPS37B.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/1335_VPS37B%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBL1-17749-img0002.jpg)