TLR1

Gene Symbol	TLR1
Entrez Gene	7096
Alt Symbol	CD281, TIL, TIL. LPRS5, rsc786
Species	Human
Gene Type	protein-coding
Description	toll-like receptor 1
Other Description	toll/interleukin-1 receptor-like protein
Swissprots	Q15399 Q9UG90 D1CS41 Q32MK3 Q32MK4 O15452 D1CS39
Accessions	EAW92901 Q15399 AB445617 BAG55014 AK292982 BAF85671 AL050262 CAB43364 AW408740 BC089403 AAH89403 BC109093 AAI09094 BC109094 AAI09095 BU623316 CR533562 CAG38593 D13637 BAA02801 DQ012254 AAY85633 DQ012255 AAY85634 DQ012256 AAY85635 DQ012257 AAY85636 DQ012258 AAY85637 DQ012259 AAY85638 DQ012260 AAY85639 DQ012261 AAY85640 DQ012262 AAY85641 DQ012263 AAY85642 DQ012264 AAY85643 U88540 AAC34137 XM_005262662 XP_005262719 XM_006714028 XP_006714091 XM_011513742 XP_011512044 XM_011513743 XP_011512045 XM_011513744 XP_011512046 XM_011513745 XP_011512047 XR_925162 XR_925163 XR_925165 NM_003263 NP_003254
Function	Participates in the innate immune response to microbial agents. Specifically recognizes diacylated and triacylated lipopeptides. Cooperates with TLR2 to mediate the innate immune response to bacterial lipoproteins or lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (By similarity). {ECO:0000250}.
Subcellular Location	Cell membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}. Cytoplasmic vesicle, phagosome membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Tissue Specificity	Ubiquitous. Highly expressed in spleen, ovary, peripheral blood leukocytes, thymus and small intestine.
Top Pathways	Toll-like receptor signaling pathway, Tuberculosis

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human TLR1 full length protein - ab132066 from Abcam Category Protein Source Wheat germ Species Human

Human TLR1 peptide - ab39865 from Abcam Category Peptide Species Human

Human TLR1 protein fragment - ab152751 from Abcam Category Protein Source Wheat germ Species Human

Human TLR1 protein fragment - ab157264 from Abcam Category Protein Source NSO cells Species Human

TLR1 Antibody Blocking Peptide - LS-E3784 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

TLR1 Antibody Blocking Peptide - LS-E30187 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TLR1 Antibody Blocking Peptide - LS-E30188 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

TLR1 Recombinant Protein - H00007096-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

TLR1 Partial Recombinant Protein - H00007096-Q01 from Novus Biologicals Category Protein Prices $369.00 Sizes 10 µg Species Human

TLR1 Blocking Peptide - NBP1-77245PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TLR1 Blocking Peptide - NBP1-77244PEP from Novus Biologicals Category Peptide Prices $129.00 Sizes 50 µg Species Human

TLR1 Recombinant Protein - H00007096-G01 from Novus Biologicals Category Protein Prices $579.00 Sizes 10 µg Species Human

Recombinant Human TLR1 Fc Chimera, CF - 1484-TR-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived

Human Toll Like Receptor 1 Protein - abx069357 from Abbexa Category Protein Source E.coli Species Human

Human Toll Like Receptor 1 Protein - abx069356 from Abbexa Category Protein Source E.coli Species Human

CD281 / TLR1 - H00007096-G01 from Acris Antibodies Category Protein Prices $550.00 Sizes 10 µg Species Human

CD281 / TLR1 - H00007096-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Species Human

CD281 / TLR1 - H00007096-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Species Human

CD281 / TLR1 - H00007096-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

CD281 / TLR1 - H00007096-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

CD281 / TLR1 Control Peptide - AP10340CP-N from Acris Antibodies Category Peptide Prices $235.00 Sizes 100 µg

CD281 / TLR1 Control Peptide - AP30892CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

CD281 / TLR1 Control Peptide - AP30893CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

Toll Like Receptor 1 (TLR1), Human - 20-8236 from ARP American Research Products Category Protein Prices $369.00 Sizes 50 µg Source E.coli Species Human

Toll Like Receptor 1 (TLR1), Human - 20-8237 from ARP American Research Products Category Protein Prices $369.00 Sizes 50 µg Source E.coli Species Human

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