PFKFB1

Gene Symbol PFKFB1
Entrez Gene 5207
Alt Symbol F6PK, HL2K, PFRX
Species Human
Gene Type protein-coding
Description 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
Other Description 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1|6PF-2-K/Fru-2,6-P2ASE liver isozyme|6PF-2-K/Fru-2,6-P2ase 1|PFK/FBPase 1|fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase
Swissprots P16118 Q99951 Q5JXS5 B4DUN5 B2RA88
Accessions EAW93207 P16118 AK300724 BAG62397 AK314089 BAG36785 AL703826 BC096077 AAH96077 BC096078 AAH96078 BC096079 AAH96079 DB187700 JQ425694 AFJ19239 JQ425695 AFJ19240 M19938 AAA35818 X52638 CAA36861 XM_005262014 XP_005262071 XM_011530791 XP_011529093 XM_011530792 XP_011529094 XM_011530793 XP_011529095 XM_011530794 XP_011529096 XM_011530795 XP_011529097 XM_011530796 XP_011529098 XR_938366 NM_001271804 NP_001258733 NM_001271805 NP_001258734 NM_002625 NP_002616 NR_073450
Function Synthesis and degradation of fructose 2,6-bisphosphate.
Tissue Specificity Liver.
Top Pathways AMPK signaling pathway, Glucagon signaling pathway, Fructose and mannose metabolism

PFK-2 liv (E-16) - sc-10096 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
PFK-2 liv (E-16): sc-10096. Western blot analysis of PFK-2 liv expression in human liver (A) and rat liver (B) tissue extracts.

PFK-2 liv (H-45) - sc-48828 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
PFK-2 liv (H-45): sc-48828. Western blot analysis of PFK-2 liv expression in non-transfected: sc-117752 (A) and human PFK-2 liv transfected: sc-113498 (B) 293T whole cell lysates.

PFK-2 liv (N-13) - sc-10094 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-PFKFB1 antibody - ab155564 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC image of TPFKFB1 staining in Mouse normal liver formalin fixed paraffin embedded tissue section, performed on a Leica Bond™ system using the standard protocol B. The section was pre-treated using heat mediated antigen retrieval (EDTA based pH 9.0 solution, epitope retrieval solution 2) for 20 mins. The section was then incubated with ab155564, 1µg/ml, for 15 mins at room temperature. A Goat anti-Rabbit biotinylated secondary antibody was used to detect the primary, and visualized using an HRP conjugated ABC system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX.For other IHC staining systems (automated and non-automated) customers should optimize variable parameters such as antigen retrieval conditions, primary antibody concentration and antibody incubation times.

Anti-PFKFB1 antibody - ab154573 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PFKFB1 antibody (ab154573) at 1/1000 dilutionLane 1 : H1299 whole cell lysateLane 2 : Hela whole cell lysateLysates/proteins at 30 µg per lane.

Anti-PFKFB1 antibody - ab71625 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PFKFB1 antibody (ab71625) at 1/240 dilution + Jurkat cell line lysate at 35 µg

Anti-PFKFB1 antibody - ab72590 from Abcam

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PFKFB1 antibody (ab72590) at 1/500 dilutionLane 1 : Extracts from HeLa cellsLane 2 : Extracts from HepG2 cellsLane 3 : Extracts from COLO205 cellsLane 4 : Extracts from 293 cellsLane 5 : Extracts from 293 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-PFKFB1 antibody - N-terminal - ab71626 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PFKFB1 antibody - N-terminal (ab71626) at 1/240 dilution + Jurkat cell line lysate at 35 µg

Anti-PFKFB2 antibody - ab70175 from Abcam

Prices $380.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ICC/IF image of ab70175 stained HepG2 cells. The cells were 100% methanol fixed (5 min) and then incubated in 1%BSA / 10% normal goat serum / 0.3M glycine in 0.1% PBS-Tween for 1h to permeabilise the cells and block non-specific protein-protein interactions. The cells were then incubated with the antibody ab70175 at 5µg/ml overnight at +4°C. The secondary antibody (green) was DyLight® 488 goat anti- rabbit (ab96899) IgG (H+L) used at a 1/250 dilution for 1h. Alexa Fluor® 594 WGA was used to label plasma membranes (red) at a 1/200 dilution for 1h. DAPI was used to stain the cell nuclei (blue) at a concentration of 1.43µM.

Anti-PFKFB2 antibody - ab72937 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PFKFB2 antibody (ab72937) at 1/500 dilutionLane 1 : PFKFB2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.SecondaryGoat anti-mouse IgG (H&L)-HRP conjugate at 1/2500 dilution

Anti-PFKFB2 antibody - N-terminal - ab135821 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PFKFB2 antibody - N-terminal (ab135821) at 1/50 dilution + Mouse kidney tissue lysate at 35 µg

Anti-PFKFB3 antibody - ab96699 from Abcam

Prices $384.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PFKFB3 antibody (ab96699) at 1/1000 dilutionLane 1 : A431 whole cell lysateLane 2 : H1299 whole cell lysateLysates/proteins at 30 µg per lane.

Anti-PFKFB3 antibody - ab113107 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
ab113107 at 1/100 dilution staining PFKFB3 in Formalin-fixed, Paraffin-embedded Human Fetal stomach tissue by Immunohistochemistry.

Anti-PFKFB3 antibody [EPR12594] - ab181861 from Abcam

Prices $384.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR12594
All lanes : Anti-PFKFB3 antibody [EPR12594] (ab181861) at 1/20000 dilutionLane 1 : Jurkat cell lysateLane 2 : HeLa cell lysateLysates/proteins at 20 µg per lane.SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugate at 1/1000 dilution

Anti-PFKFB3 antibody - C-terminal - ab135820 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PFKFB3 antibody - C-terminal (ab135820) at 1/100 dilution + CEM cell lysate at 35 µg

Anti-PFKFB3 antibody - Carboxyterminal end - ab55944 from Abcam

Prices $372.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PFKFB4 antibody - ab71622 from Abcam

Prices $394.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-PFKFB4 antibody (ab71622) at 1/100 dilution + mouse brain tissue lysate at 12.5 µg

Anti-PFKFB4 antibody [1C8] - ab113934 from Abcam

Prices $376.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 1C8
Immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PFKFB4 using ab113934 at a dilution of 1/100.

Anti-PFKFB1 Antibody (AP) - LS-C226101 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB1 Antibody (APC) - LS-C226102 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB1 Antibody (Biotin) - LS-C226103 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB1 Antibody (FITC) - LS-C226104 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PFKFB1 Antibody (aa335-384) - LS-C145350 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PFKFB1 antibody LS-C145350 Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.

Anti-PFKFB1 Antibody (C-Terminus) - LS-C145349 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
PFKFB1 antibody LS-C145349 Western blot of 1 Cell lysate. Antibody concentration 1 ug/ml.

Anti-PFKFB1 Antibody (N-Terminus, AP) - LS-C226105 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
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