Gene Symbol | PFKFB1 |
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Entrez Gene | 5207 |
Alt Symbol | F6PK, HL2K, PFRX |
Species | Human |
Gene Type | protein-coding |
Description | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 |
Other Description | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1|6PF-2-K/Fru-2,6-P2ASE liver isozyme|6PF-2-K/Fru-2,6-P2ase 1|PFK/FBPase 1|fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase |
Swissprots | P16118 Q99951 Q5JXS5 B4DUN5 B2RA88 |
Accessions | EAW93207 P16118 AK300724 BAG62397 AK314089 BAG36785 AL703826 BC096077 AAH96077 BC096078 AAH96078 BC096079 AAH96079 DB187700 JQ425694 AFJ19239 JQ425695 AFJ19240 M19938 AAA35818 X52638 CAA36861 XM_005262014 XP_005262071 XM_011530791 XP_011529093 XM_011530792 XP_011529094 XM_011530793 XP_011529095 XM_011530794 XP_011529096 XM_011530795 XP_011529097 XM_011530796 XP_011529098 XR_938366 NM_001271804 NP_001258733 NM_001271805 NP_001258734 NM_002625 NP_002616 NR_073450 |
Function | Synthesis and degradation of fructose 2,6-bisphosphate. |
Tissue Specificity | Liver. |
Top Pathways | AMPK signaling pathway, Glucagon signaling pathway, Fructose and mannose metabolism |
PFK-2 liv CRISPR/Cas9 KO Plasmid (h) - sc-405447 from Santa Cruz Biotechnology
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PFK-2 liv HDR Plasmid (h) - sc-405447-HDR from Santa Cruz Biotechnology
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PFK-2 liv Double Nickase Plasmid (h) - sc-405447-NIC from Santa Cruz Biotechnology
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PFK-2 liv Double Nickase Plasmid (h2) - sc-405447-NIC-2 from Santa Cruz Biotechnology
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PFK-2 liv CRISPR Activation Plasmid (h) - sc-405447-ACT from Santa Cruz Biotechnology
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PFK-2 liv CRISPR Activation Plasmid (h2) - sc-405447-ACT-2 from Santa Cruz Biotechnology
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PFK-2 liv Lentiviral Activation Particles (h) - sc-405447-LAC from Santa Cruz Biotechnology
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PFK-2 liv Lentiviral Activation Particles (h2) - sc-405447-LAC-2 from Santa Cruz Biotechnology
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PFK-2 liv siRNA (h) - sc-39032 from Santa Cruz Biotechnology
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PFK-2 liv shRNA Plasmid (h) - sc-39032-SH from Santa Cruz Biotechnology
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PFK-2 liv shRNA (h) Lentiviral Particles - sc-39032-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU005211 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0393 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0392 from Sigma-Aldrich
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MISSION® Human Phosphatase - SIHP0391 from Sigma-Aldrich
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MISSION® siRNA - SIHK1576 from Sigma-Aldrich
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MISSION® siRNA - SIHK1575 from Sigma-Aldrich
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MISSION® siRNA - SIHK1574 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN16654 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16654 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR01157 from Sigma-Aldrich
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PFKFB1 siRNA (Human) - CRH3477 from Cohesion Biosciences
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PFKFB1 RNAi - H00005207-R03 from Novus Biologicals
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shRNA set against Human PFKFB1(NM_002625.2) - SHR107484 from Creative biogene
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PFKFB1 shRNA Plasmid (Human) - CHH3477 from Cohesion Biosciences
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