UNC5D

Gene Symbol UNC5D
Entrez Gene 137970
Alt Symbol PRO34692, Unc5h4
Species Human
Gene Type protein-coding
Description unc-5 homolog D (C. elegans)
Other Description netrin receptor UNC5D|netrin receptor Unc5h4|protein unc-5 homolog 4|protein unc-5 homolog D|unc-5 homolog 4
Swissprots Q8WYP7 Q6UXZ4
Accessions EAW63381 EAW63382 EAW63383 Q6UXZ4 AB055056 BAB83663 AB073394 AK092313 AK122610 BAG53621 AK122615 AY358147 AAQ88514 BC156113 AAI56114 BC156908 AAI56909 BY798317 XM_006716288 XP_006716351 XM_011544398 XP_011542700 XM_011544399 XP_011542701 XM_011544400 XP_011542702 XM_011544401 XP_011542703 XM_011544402 XP_011542704 XM_011544403 XP_011542705 XM_011544404 XP_011542706 XM_011544405 XP_011542707 NM_080872 NP_543148
Function Receptor for netrin. May be involved in axon guidance by mediating axon repulsion of neuronal growth cones in the developing nervous system upon ligand binding. Axon repulsion in growth cones may be caused by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand (By similarity). {ECO:0000250}.
Subcellular Location Membrane {ECO:0000250}; Single-pass type I membrane protein {ECO:0000250}.
Top Pathways Axon guidance

UNC5H4 (H-57) - sc-135262 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
UNC5H4 (H-57): sc-135262. Western blot analysis of UNC5H4 expression in mouse brain tissue extract.

UNC5H4 (N-20) - sc-67978 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UNC5H4 (N-20): sc-67978. Western blot analysis of UNC5H4 expression in K-562 (A), HEK293 (B), HeLa (C) and Jurkat (D) whole cell lysates.

UNC5H4 (T-20) - sc-67979 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

UNC5H4 (Y-18) - sc-67980 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
UNC5H4 (Y-18): sc-67980. Western blot analysis of UNC5H4 expression in HEK293 (A) and HeLa (B) whole cell lysates.

Anti-UNC5D antibody - ab58141 from Abcam

Prices $385.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing SH-SY5Y cells stained with ab58141 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions. The cells were then incubated with the antibody (ab58141, 0.1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was Alexa Fluor® 488 goat anti-mouse IgG (H+L) (ab150113) at 1/2000 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive result in 80% methanol (5 min) fixed SH-SY5Y cells used under the same conditions. Please note that Abcam do not have any data for use of this antibody on non-fixed cells. We welcome any customer feedback.

Anti-UNC5D Antibody (aa483-511, APC) - LS-C273059 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC5D Antibody (aa483-511, AP) - LS-C273057 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC5D Antibody (aa483-511, Biotin) - LS-C273060 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC5D Antibody (aa483-511, FITC) - LS-C273061 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC5D Antibody (aa483-511, Azide-free, HRP) - LS-C273062 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC5D Antibody (aa483-511, PE) - LS-C273063 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC5D Antibody (aa482-511) - LS-C326198 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-UNC5D Antibody (aa483-511) - LS-C160437 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
UNC5D Antibody western blot of 293 cell line lysates (35 ug/lane). The UNC5D antibody detected the UNC5D protein (arrow).

UNC5H4/UNC5D Antibody - AF1429 from Novus Biologicals

Prices $99.00, $359.00
Sizes 25 µg, 100 µg
Host Goat
Clonality Polyclonal

UNC5H4/UNC5D Antibody - NBP1-92562 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: UNC5D Antibody [NBP1-92562] - Staining of human cell line U-251 MG shows positivity in nucleus but not nucleoli.

UNC5H4/UNC5D Antibody (4G3) - H00137970-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4G3
Sandwich ELISA: UNC5H4/UNC5D Antibody (4G3) [H00137970-M01] - Detection limit for recombinant GST tagged UNC5D is approximately 0.03ng/ml as a capture antibody.

UNC5H4/UNC5D Antibody - H00137970-A01 from Novus Biologicals

Prices $269.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal

UNC5H4/UNC5D Antibody [Biotin] - BAF1429 from Novus Biologicals

Prices $390.00
Sizes 50 µg
Host Goat
Clonality Polyclonal

UNC5D/UNC5H4 Polyclonal Antibody - bs-11494R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC5D/UNC5H4 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-11494R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC5D/UNC5H4 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-11494R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC5D/UNC5H4 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-11494R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC5D/UNC5H4 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-11494R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC5D/UNC5H4 Polyclonal Antibody, Cy3 Conjugated - bs-11494R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

UNC5D/UNC5H4 Polyclonal Antibody, Cy5 Conjugated - bs-11494R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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