| Gene Symbol |
Bmpr1a
|
| Entrez Gene |
81507
|
| Alt Symbol |
-
|
| Species |
Rat
|
| Gene Type |
protein-coding
|
| Description |
bone morphogenetic protein receptor, type IA
|
| Other Description |
ALK-3|BMP type-1A receptor|BMPR-1A|activin receptor-like kinase 3|bone morphogenetic protein 4 receptor|bone morphogenetic protein receptor type-1A|bone morphogenetic protein receptor, type 1A
|
| Swissprots |
Q78EA7 Q64308
|
| Accessions |
CAT04595 EDL88873 Q78EA7 D17667 BAA04549 D38082 BAA07275 S75359 AAB33865 NM_030849 NP_110476
|
| Function |
On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4 (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells
|
