| Gene Symbol | Bmpr1a |
|---|---|
| Entrez Gene | 81507 |
| Alt Symbol | - |
| Species | Rat |
| Gene Type | protein-coding |
| Description | bone morphogenetic protein receptor, type IA |
| Other Description | ALK-3|BMP type-1A receptor|BMPR-1A|activin receptor-like kinase 3|bone morphogenetic protein 4 receptor|bone morphogenetic protein receptor type-1A|bone morphogenetic protein receptor, type 1A |
| Swissprots | Q78EA7 Q64308 |
| Accessions | CAT04595 EDL88873 Q78EA7 D17667 BAA04549 D38082 BAA07275 S75359 AAB33865 NM_030849 NP_110476 |
| Function | On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for BMP-2 and BMP-4 (By similarity). {ECO:0000250}. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Cytokine-cytokine receptor interaction, TGF-beta signaling pathway, Hippo signaling pathway, Signaling pathways regulating pluripotency of stem cells |