AGPAT1

Gene Symbol AGPAT1
Entrez Gene 10554
Alt Symbol 1-AGPAT1, G15, LPAAT-alpha, LPAATA
Species Human
Gene Type protein-coding
Description 1-acylglycerol-3-phosphate O-acyltransferase 1
Other Description 1-AGP acyltransferase 1|1-AGPAT 1|1-acyl-sn-glycerol-3-phosphate acyltransferase alpha|1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase)|1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)|lysophosphatidic acid acyltransferase alpha|lysophospholipid acyltransferase
Swissprots Q99943 Q5BL03 A2BFI5
Accessions AAB47493 EAX03599 EAX03600 EAX03601 EAX03602 EAX03603 EAX03604 EAX03605 EAX03606 Q99943 AF007145 AAC19153 AF218034 AAG17276 AI193422 AK056346 BAG51685 AK058025 AK129818 AK299252 BAG61283 AK315950 BAH14321 BC002402 AAH02402 BC003007 AAH03007 BC004310 AAH04310 BC006818 BC090849 AAH90849 BM763275 DA529681 DB118884 U56417 AAB58775 U75971 AAB96378 Y09565 CAA70758 XM_005248805 XP_005248862 XM_005248806 XP_005248863 XM_005272761 XP_005272818 XM_005272762 XP_005272819 XM_005274829 XP_005274886 XM_005274830 XP_005274887 XM_005275073 XP_005275130 XM_005275074 XP_005275131 XM_005275203 XP_005275260 XM_005275204 XP_005275261 XM_005275337 XP_005275394 XM_005275338 XP_005275395 XM_005275504 XP_005275561 XM_005275505 XP_005275562 XM_011514234 XP_011512536 XM_011546281 XP_011544583 XM_011547171 XP_011545473 XM_011547825 XP_011546127 XM_011548005 XP_011546307 XM_011548182 XP_011546484 XM_011548377 XP_011546679 NM_006411 NP_006402 NM_032741 NP_116130
Function Converts lysophosphatidic acid (LPA) into phosphatidic acid by incorporating an acyl moiety at the sn-2 position of the glycerol backbone. {ECO:0000269|PubMed:21873652}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:21873652}; Multi-pass membrane protein {ECO:0000269|PubMed:21873652}.
Tissue Specificity Widely expressed. Expressed in adipose tissue and at high levels in testis and pancreas. Expressed at lower levels in tissues such as heart, brain, placenta, kidney, lung, spleen, thymus, prostate, ovary, intestine, colon, leukocyte and liver. {ECO:0000269|PubMed:21873652}.
Top Pathways Fat digestion and absorption, Glycerolipid metabolism, Glycerophospholipid metabolism

LPAAT-α CRISPR/Cas9 KO Plasmid (h) - sc-406544 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α HDR Plasmid (h) - sc-406544-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α Double Nickase Plasmid (h) - sc-406544-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α Double Nickase Plasmid (h2) - sc-406544-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α CRISPR Activation Plasmid (h) - sc-406544-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α CRISPR Activation Plasmid (h2) - sc-406544-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α Lentiviral Activation Particles (h) - sc-406544-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α Lentiviral Activation Particles (h2) - sc-406544-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

LPAAT-α siRNA (h) - sc-75692 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LPAAT-α shRNA Plasmid (h) - sc-75692-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

LPAAT-α shRNA (h) Lentiviral Particles - sc-75692-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU228041 from Sigma-Aldrich

Category siRNA
Prices $140.00, $140.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN2948 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND2948 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR07597 from Sigma-Aldrich

Category miRNA

AGPAT1 siRNA (Human) - CRH7175 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

AGPAT1 RNAi - H00010554-R02 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AGPAT1 RNAi - H00010554-R01 from Novus Biologicals

Category siRNA
Prices $399.00
Sizes 20 nmol
Species Reactivities Human

AGPAT1 - MBS8230793 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human AGPAT1 (NM_006411.3) - SHH233322 from Creative biogene

Category siRNA
Species Reactivities Human

AGPAT1 shRNA Plasmid (Human) - CHH7175 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

AGPAT1 miRNA 3'UTR clone - MiUTR3H-05665 from Creative biogene

Species Reactivities Human

AGPAT1 miRNA 3'UTR clone - MiUTR3H-05666 from Creative biogene

Species Reactivities Human
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