| Gene Symbol |
RSF1
|
| Entrez Gene |
51773
|
| Alt Symbol |
HBXAP, RSF-1, XAP8, p325
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
remodeling and spacing factor 1
|
| Other Description |
HBV pX associated protein-8|HBV pX-associated protein 8|hepatitis B virus x associated protein|hepatitis B virus x-associated protein|p325 subunit of RSF chromatin-remodeling complex
|
| Swissprots |
Q9NYU0 Q9H3L8 Q96T23 Q86X86 Q9NVZ8
|
| Accessions |
EAW75033 EAW75034 EAW75035 Q96T23 AF059317 AAG43114 AF227948 AAF61709 AF380176 AAK57515 AK001268 BAA91591 AK096617 AK098130 AL602953 BC000774 BC011205 BC015360 AAH15360 BC046124 AAH46124 BC046347 BC148326 AAI48327 BC153210 AAI53211 XM_005274051 XP_005274108 NM_016578 NP_057662
|
| Function |
Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF- alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. {ECO:0000269|PubMed:11788598, ECO:0000269|PubMed:12972596}.
|
| Subcellular Location |
Nucleus {ECO:0000269|PubMed:11788598, ECO:0000269|PubMed:11944984}.
|
| Tissue Specificity |
Ubiquitously expressed.
|
![Western Blot: RSF1 Overexpression Lysate (Adult Normal) [NBP2-07015] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RSF1.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/9840_RSF1%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07015-img0001.jpg)