Gene Symbol | RSF1 |
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Entrez Gene | 51773 |
Alt Symbol | HBXAP, RSF-1, XAP8, p325 |
Species | Human |
Gene Type | protein-coding |
Description | remodeling and spacing factor 1 |
Other Description | HBV pX associated protein-8|HBV pX-associated protein 8|hepatitis B virus x associated protein|hepatitis B virus x-associated protein|p325 subunit of RSF chromatin-remodeling complex |
Swissprots | Q9NYU0 Q9H3L8 Q96T23 Q86X86 Q9NVZ8 |
Accessions | EAW75033 EAW75034 EAW75035 Q96T23 AF059317 AAG43114 AF227948 AAF61709 AF380176 AAK57515 AK001268 BAA91591 AK096617 AK098130 AL602953 BC000774 BC011205 BC015360 AAH15360 BC046124 AAH46124 BC046347 BC148326 AAI48327 BC153210 AAI53211 XM_005274051 XP_005274108 NM_016578 NP_057662 |
Function | Required for assembly of regular nucleosome arrays by the RSF chromatin-remodeling complex. Facilitates transcription of hepatitis B virus (HBV) genes by the pX transcription activator. In case of infection by HBV, together with pX, it represses TNF- alpha induced NF-kappa-B transcription activation. Represses transcription when artificially recruited to chromatin by fusion to a heterogeneous DNA binding domain. {ECO:0000269|PubMed:11788598, ECO:0000269|PubMed:12972596}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11788598, ECO:0000269|PubMed:11944984}. |
Tissue Specificity | Ubiquitously expressed. |
XAP8 CRISPR/Cas9 KO Plasmid (h) - sc-412247 from Santa Cruz Biotechnology
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XAP8 HDR Plasmid (h) - sc-412247-HDR from Santa Cruz Biotechnology
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XAP8 Double Nickase Plasmid (h) - sc-412247-NIC from Santa Cruz Biotechnology
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XAP8 Double Nickase Plasmid (h2) - sc-412247-NIC-2 from Santa Cruz Biotechnology
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XAP8 CRISPR Activation Plasmid (h) - sc-412247-ACT from Santa Cruz Biotechnology
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XAP8 CRISPR Activation Plasmid (h2) - sc-412247-ACT-2 from Santa Cruz Biotechnology
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XAP8 Lentiviral Activation Particles (h) - sc-412247-LAC from Santa Cruz Biotechnology
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XAP8 Lentiviral Activation Particles (h2) - sc-412247-LAC-2 from Santa Cruz Biotechnology
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Rsf-1 siRNA (h) - sc-72261 from Santa Cruz Biotechnology
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Rsf-1 shRNA Plasmid (h) - sc-72261-SH from Santa Cruz Biotechnology
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Rsf-1 shRNA (h) Lentiviral Particles - sc-72261-V from Santa Cruz Biotechnology
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RSF1 RNAi - H00051773-R01 from Novus Biologicals
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MISSION® esiRNA - EHU059911 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN18708 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND18708 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR05914 from Sigma-Aldrich
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RSF1 siRNA (Human) - CRH9944 from Cohesion Biosciences
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RSF1 - MBS8212219 from MyBioSource
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shRNA set against Human RSF1(NM_016578.3) - SHR199668 from Creative biogene
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RSF1 shRNA Plasmid (Human) - CHH9944 from Cohesion Biosciences
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RSF1 miRNA 3'UTR clone - MiUTR1H-09054 from Creative biogene
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