| Gene Symbol |
GJC2
|
| Entrez Gene |
57165
|
| Alt Symbol |
CX46.6, Cx47, GJA12, HLD2, LMPH1C, PMLDAR, SPG44
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
gap junction protein, gamma 2, 47kDa
|
| Other Description |
connexin-46.6|connexin-47|gap junction alpha-12 protein|gap junction gamma-2 protein
|
| Swissprots |
Q8IWJ9 O43440 Q7Z7J2 Q5T442
|
| Accessions |
AAB94511 EAW69860 Q5T442 AY285161 AAP37488 BC035840 AAH35840 BC089439 AAH89439 BU739494 CF132637 EU433401 ACB87443 NM_020435 NP_065168
|
| Function |
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. {ECO:0000269|PubMed:15192806}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein. Cell junction, gap junction.
|
| Tissue Specificity |
Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles. {ECO:0000269|PubMed:15192806}.
|