Gene Symbol | GJC2 |
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Entrez Gene | 57165 |
Alt Symbol | CX46.6, Cx47, GJA12, HLD2, LMPH1C, PMLDAR, SPG44 |
Species | Human |
Gene Type | protein-coding |
Description | gap junction protein, gamma 2, 47kDa |
Other Description | connexin-46.6|connexin-47|gap junction alpha-12 protein|gap junction gamma-2 protein |
Swissprots | Q8IWJ9 O43440 Q7Z7J2 Q5T442 |
Accessions | AAB94511 EAW69860 Q5T442 AY285161 AAP37488 BC035840 AAH35840 BC089439 AAH89439 BU739494 CF132637 EU433401 ACB87443 NM_020435 NP_065168 |
Function | One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a role in myelination in central and peripheral nervous systems. {ECO:0000269|PubMed:15192806}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. Cell junction, gap junction. |
Tissue Specificity | Expressed in central nervous system, in sciatic nerve and sural nerve. Also detected in skeletal muscles. {ECO:0000269|PubMed:15192806}. |
connexin 47 CRISPR/Cas9 KO Plasmid (h) - sc-412768 from Santa Cruz Biotechnology
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connexin 47 HDR Plasmid (h) - sc-412768-HDR from Santa Cruz Biotechnology
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connexin 47 Double Nickase Plasmid (h) - sc-412768-NIC from Santa Cruz Biotechnology
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connexin 47 Double Nickase Plasmid (h2) - sc-412768-NIC-2 from Santa Cruz Biotechnology
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connexin 47 CRISPR Activation Plasmid (h) - sc-412768-ACT from Santa Cruz Biotechnology
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connexin 47 CRISPR Activation Plasmid (h2) - sc-412768-ACT-2 from Santa Cruz Biotechnology
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connexin 47 Lentiviral Activation Particles (h) - sc-412768-LAC from Santa Cruz Biotechnology
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connexin 47 Lentiviral Activation Particles (h2) - sc-412768-LAC-2 from Santa Cruz Biotechnology
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connexin 47 siRNA (h) - sc-105232 from Santa Cruz Biotechnology
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connexin 47 shRNA Plasmid (h) - sc-105232-SH from Santa Cruz Biotechnology
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connexin 47 shRNA (h) Lentiviral Particles - sc-105232-V from Santa Cruz Biotechnology
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GJC2 RNAi - H00057165-R01 from Novus Biologicals
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MISSION® esiRNA - EHU159701 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN9316 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND9316 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR06006 from Sigma-Aldrich
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GJC2 siRNA (Human) - CRJ1370 from Cohesion Biosciences
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GJC2 - MBS828668 from MyBioSource
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shRNA set against Human GJC2 (NM_020435.3) - SHH301454 from Creative biogene
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Human GJC2 siRNA - orb271871 from Biorbyt
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GJC2 shRNA Plasmid (Human) - CHJ1370 from Cohesion Biosciences
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GJC2 miRNA 3'UTR clone - MiUTR4H-TG03831 from Creative biogene
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