Gene Symbol | C1QB |
---|---|
Entrez Gene | 713 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | complement component 1, q subcomponent, B chain |
Other Description | complement C1q subcomponent subunit B|complement component 1, q subcomponent, beta polypeptide|complement component C1q, B chain|complement subcomponent C1q chain B |
Swissprots | Q5T959 P02746 Q96H17 |
Accessions | AAQ67338 EAW95019 EAW95020 EAW95021 P02746 BC008983 AAH08983 BQ711602 DQ891531 ABM82457 DQ894720 ABM85646 M36278 AAC41692 X03084 CAA26880 XM_011542059 XP_011540361 NM_000491 NP_000482 |
Function | C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes. |
Subcellular Location | Secreted. |
Top Pathways | Complement and coagulation cascades, Systemic lupus erythematosus, Prion diseases, Chagas disease (American trypanosomiasis), Staphylococcus aureus infection |
Human C1QB full length protein - ab157983 from Abcam
|
||||||||||
Recombinant Human C1QB Protein - H00000713-P01 from Novus Biologicals
|
||||||||||
C1QB-Antibody-N-term-Blocking-Peptide - BP8893a from Abgent, a WuXi AppTec company
|
||||||||||
Human C1QB His tag protein - orb83972 from Biorbyt
|
||||||||||
C1QB Blocking Peptide - 33R-7122 from Fitzgerald
|
||||||||||
C1QB Blocking Peptide - 33R-1631 from Fitzgerald
|
||||||||||
C1q B subunit - H00000713-P01-10 from Acris Antibodies
|
||||||||||
C1q B subunit - H00000713-P01-25 from Acris Antibodies
|
||||||||||
C1QB fusion protein - ag10225 from Proteintech Group
|
||||||||||
C1QB fusion protein - Ag10622 from Proteintech Group
|
||||||||||
Recombinant Human C1QB, His tagged - C1QB-596H from Creative Biomart
|
||||||||||
Human C1QB / C1qB Protein (His Tag) - 10941-H08B-100 from Sino Biological
|
||||||||||
C1q-B (V193) Peptide - BS3288P from Bioworld Technology
|
||||||||||
Recombinant Human Complement C1q subcomponent subunit B(C1QB) - CSB-YP003638HU CSB-EP003638HU CSB-BP003638HU CSB-MP003638HU from Cusabio
|
||||||||||
C1q B subunit - TP303821 from Acris Antibodies
|
||||||||||
Native Human Complement Component C1q - CRC162A from Cell Science
|
||||||||||
Native Human Complement Component C1q - CRC162B from Cell Science
|
||||||||||
Native Human Complement Component C1q - CRC162C from Cell Science
|
||||||||||
Recombinant Human C1QB / C1qB Protein (His tag) - PKSH031345 from Elabscience
|
||||||||||
C1QB Recombinant Protein Antigen - NBP2-49033PEP from Novus Biologicals
|
||||||||||
C1QB Peptide, Human - M34GP01917H from Creative Peptides
|
||||||||||
Complement C1QB Blocking Peptide - CBP4584 from Cohesion Biosciences
|
||||||||||
Human C1QB / C1qB Protein (His Tag) - 10941-H08B from ABclonal
|
||||||||||
Complement C1QB Blocking Peptide - orb392929 from Biorbyt
|
||||||||||
C1QB / C1qB, Recombinant Protein - MBS2546002 from MyBioSource
|