ESCO1

Gene Symbol ESCO1
Entrez Gene 114799
Alt Symbol A930014I12Rik, CTF, ECO1, EFO1, ESO1
Species Human
Gene Type protein-coding
Description establishment of sister chromatid cohesion N-acetyltransferase 1
Other Description CTF7 homolog 1|ECO1 homolog 1|EFO1p|ESO1 homolog 1|N-acetyltransferase ESCO1|establishment factor-like protein 1|establishment of cohesion 1 homolog 1|hEFO1
Swissprots Q69YG4 Q8N3Z5 B0YJ11 Q69YS3 Q96PX7 Q5FWF5 Q6IMD7 B0YJ12 Q8NBG2
Accessions ACA05989 EAX01127 EAX01128 EAX01129 Q5FWF5 AB067498 BAB67804 AK090579 BAC03483 AK096746 AL832041 CAH10584 AL834200 CAH10682 BC036943 AAH36943 BC089426 AAH89426 BG492713 BK001617 DAA02068 XM_011525798 XP_011524100 XM_011525799 XP_011524101 XR_935191 NM_052911 NP_443143
Function Acetyltransferase required for the establishment of sister chromatid cohesion and couple the processes of cohesion and DNA replication to ensure that only sister chromatids become paired together. In contrast to the structural cohesins, the deposition and establishment factors are required only during S phase. Acts by mediating the acetylation of cohesin component SMC3. {ECO:0000269|PubMed:14576321, ECO:0000269|PubMed:15958495, ECO:0000269|PubMed:18614053, ECO:0000269|PubMed:19907496}.
Subcellular Location Nucleus. Chromosome. Note=Nuclear at interphase, associated with chromosomes during mitosis.
Tissue Specificity Widely expressed. Expressed in heart, brain, liver, placenta, lung, kidney and pancreas. Highly expressed in muscle. {ECO:0000269|PubMed:14576321}.

EFO1 CRISPR/Cas9 KO Plasmid (h) - sc-414046 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 HDR Plasmid (h) - sc-414046-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 Double Nickase Plasmid (h) - sc-414046-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 Double Nickase Plasmid (h2) - sc-414046-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 CRISPR Activation Plasmid (h) - sc-414046-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 CRISPR Activation Plasmid (h2) - sc-414046-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 Lentiviral Activation Particles (h) - sc-414046-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 Lentiviral Activation Particles (h2) - sc-414046-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

EFO1 siRNA (h) - sc-62257 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EFO1 shRNA Plasmid (h) - sc-62257-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

EFO1 shRNA (h) Lentiviral Particles - sc-62257-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU015731 from Sigma-Aldrich

Category siRNA
Prices $250.00
Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7982 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7982 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

ESCO1 siRNA (Human) - CRJ4383 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ESCO1 - MBS8209680 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ESCO1 (NM_052911.2) - SHH287305 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human ESCO1(NM_052911.2) - SHG210355 from Creative biogene

Category siRNA
Species Reactivities Human

ESCO1 shRNA Plasmid (Human) - CHJ4383 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ESCO1 miRNA 3'UTR clone - MiUTR1H-03307 from Creative biogene

Species Reactivities Human
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