Gene Symbol | CDT1 |
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Entrez Gene | 81620 |
Alt Symbol | DUP, RIS2 |
Species | Human |
Gene Type | protein-coding |
Description | chromatin licensing and DNA replication factor 1 |
Other Description | DNA replication factor Cdt1|Double parked, Drosophila, homolog of |
Swissprots | Q9BWM0 Q96HE6 Q96CJ5 Q96H67 Q9H211 Q86XX9 Q96GK5 |
Accessions | EAW66762 EAW66763 EAW66764 Q9H211 AB053172 BAB61878 AF070552 AF321125 AAG45181 BC000137 AAH00137 BC008676 AAH08676 BC008860 AAH08860 BC009410 AAH09410 BC014202 AAH14202 BC021126 AAH21126 BC049205 AAH49205 NM_030928 NP_112190 |
Function | Cooperates with CDC6 to promote the loading of the mini- chromosome maintenance complex onto chromatin to form the pre- replication complex necessary to initiate DNA replication. Binds DNA in a sequence-, strand-, and conformation-independent manner. Potential oncogene. {ECO:0000250|UniProtKB:Q8R4E9, ECO:0000269|PubMed:11125146, ECO:0000269|PubMed:14672932, ECO:0000269|PubMed:14993212, ECO:0000269|PubMed:21856198}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:11125146}. |
Cdt1 CRISPR/Cas9 KO Plasmid (h) - sc-401014 from Santa Cruz Biotechnology
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Cdt1 HDR Plasmid (h) - sc-401014-HDR from Santa Cruz Biotechnology
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Cdt1 Double Nickase Plasmid (h) - sc-401014-NIC from Santa Cruz Biotechnology
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Cdt1 Double Nickase Plasmid (h2) - sc-401014-NIC-2 from Santa Cruz Biotechnology
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Cdt1 CRISPR Activation Plasmid (h) - sc-401014-ACT from Santa Cruz Biotechnology
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Cdt1 CRISPR Activation Plasmid (h2) - sc-401014-ACT-2 from Santa Cruz Biotechnology
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Cdt1 Lentiviral Activation Particles (h) - sc-401014-LAC from Santa Cruz Biotechnology
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Cdt1 Lentiviral Activation Particles (h2) - sc-401014-LAC-2 from Santa Cruz Biotechnology
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Cdt1 siRNA (h) - sc-37544 from Santa Cruz Biotechnology
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Cdt1 shRNA Plasmid (h) - sc-37544-SH from Santa Cruz Biotechnology
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Cdt1 shRNA (h) Lentiviral Particles - sc-37544-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU057961 from Sigma-Aldrich
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MISSION® esiRNA - EHU054811 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN5886 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5886 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR07757 from Sigma-Aldrich
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CDT1 siRNA (Human) - CRJ3028 from Cohesion Biosciences
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CDT1 - MBS8215600 from MyBioSource
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Cdt1 CRISPR/Cas9 KO Plasmid (h2) - sc-401014-KO-2 from Santa Cruz Biotechnology
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Cdt1 HDR Plasmid (h2) - sc-401014-HDR-2 from Santa Cruz Biotechnology
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shRNA set against Human CDT1 (NM_030928.3) - SHH261053 from Creative biogene
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Human CDT1 siRNA - orb273529 from Biorbyt
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CDT1 shRNA Plasmid (Human) - CHJ3028 from Cohesion Biosciences
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CDT1 miRNA 3'UTR clone - MiUTR3H-07762 from Creative biogene
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