Gene Symbol | Scarb1 |
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Entrez Gene | 20778 |
Alt Symbol | AI120173, CD36, Cd36l1, Cla-1, Cla1, D5Ertd460e, Hdlq1, Hlb398, SR-B1, SR-BI, SRBI, Srb1, mSR-BI |
Species | Mouse |
Gene Type | protein-coding |
Description | scavenger receptor class B, member 1 |
Other Description | HDL QTL 1|scavenger receptor class B member 1|scavenger receptor class B type I|scavenger receptor class B1 |
Swissprots | Q9CWJ7 Q61009 |
Accessions | EDL19562 EDL19563 Q61009 AK010622 BAB27068 AK028191 BAC25802 AK033114 BAC28157 AK080894 BAC38067 AK143368 AK145588 AK154933 BAE32934 AK158122 BAE34368 AK169906 BAE41449 AK171602 AK185019 AK187730 AK189473 AK196382 AK197937 AK199031 AK201170 AK202996 AK204897 AK212899 BC004656 AAH04656 BQ176029 BY018765 CT010222 CAJ18430 U37799 AAC52378 XM_006504285 XP_006504348 XM_006504286 XP_006504349 NM_001205082 NP_001192011 NM_001205083 NP_001192012 NM_016741 NP_058021 |
Function | Receptor for different ligands such as phospholipids, cholesterol ester, lipoproteins, phosphatidylserine and apoptotic cells. Probable receptor for HDL, located in particular region of the plasma membrane, called caveolae. Facilitates the flux of free and esterified cholesterol between the cell surface and extracellular donors and acceptors, such as HDL and to a lesser extent, apoB-containing lipoproteins and modified lipoproteins. Probably involved in the phagocytosis of apoptotic cells, via its phosphatidylserine binding activity (By similarity). Plays an important role in the uptake of HDL cholesteryl ester (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Membrane, caveola {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}. Note=Predominantly localized to cholesterol and sphingomyelin-enriched domains within the plasma membrane, called caveolae. {ECO:0000250}. |
Tissue Specificity | Expressed primarily in liver and non-placental steroidogenic tissues. |
Top Pathways | Phagosome, Hepatitis C, Bile secretion, Fat digestion and absorption, Vitamin digestion and absorption |
Mouse SCARB1 Fc His tag protein - orb83310 from Biorbyt
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Recombinant Mouse Scarb1, Fc-tagged - Scarb1-01M from Creative Biomart
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Recombinant Mouse Scarb1, His tagged - Scarb1-849M from Creative Biomart
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Recombinant Mouse Scarb1, His-tagged - Scarb1-3294M from Creative Biomart
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Mouse SR-BI Recombinant - RKQ61009 from Reprokine
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Mouse CD36 / SCARB3 Protein (His Tag) - 50422-M08H-50 from Sino Biological
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Mouse CD36 / SCARB3 Protein (His & Fc Tag) - 50422-M03H-50 from Sino Biological
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Mouse SCARB1 / CD36L1 / CLA-1 Protein (His & Fc Tag) - 50317-M03H-20 from Sino Biological
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Mouse SCARB1 / CD36L1 / CLA-1 Protein (His Tag) - 50317-M08H-20 from Sino Biological
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Recombinant Platelet Membrane Glycoprotein IV (GP4) - RPB530Mu01 from Cloud-clone
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Recombinant Mouse CD36 / SCARB3 Protein (His tag) - PKSM040689 from Elabscience
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Recombinant Mouse CD36 / SCARB3 Protein (His & Fc tag) - PKSM040690 from Elabscience
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Recombinant Mouse SCARB1 / CD36L1 / CLA-1 Protein (His tag) - PKSM040740 from Elabscience
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Recombinant Mouse SCARB1 / CD36L1 / CLA-1 Protein (His & Fc tag) - PKSM040741 from Elabscience
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Mouse SCARB1 His tag protein - orb83311 from Biorbyt
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Platelet glycoprotein 4 - PAT-83159-2 from Nordic BioSite
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Platelet glycoprotein 4 - PAT-83159-1 from Nordic BioSite
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Mouse SCARB1 / CD36L1 / CLA-1 Protein (His & Fc Tag) - 50317-M03H from ABclonal
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Mouse SCARB1 / CD36L1 / CLA-1 Protein (His Tag) - 50317-M08H from ABclonal
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Mouse CD36 / SCARB3 Protein (His & Fc Tag) - 50422-M03H from ABclonal
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Mouse CD36 / SCARB3 Protein (His Tag) - 50422-M08H from ABclonal
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CD36, Mouse Recombinant - 228-22352-1 from RayBiotech
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SCARB1 / CD36L1 / CLA-1, Recombinant Protein - MBS2547039 from MyBioSource
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SCARB1 / CD36L1 / CLA-1, Recombinant Protein - MBS2547040 from MyBioSource
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