CTDSP2

Gene Symbol CTDSP2
Entrez Gene 10106
Alt Symbol OS4, PSR2, SCP2
Species Human
Gene Type protein-coding
Description CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
Other Description NLI-interacting factor 2|carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2|conserved gene amplified in osteosarcoma|nuclear LIM interactor-interacting factor 2|protein OS-4|small C-terminal domain phosphatase 2|small CTD phosphatase 2
Swissprots Q6NZY3 Q53ZR2 A8K5H4 O14595 Q9UEX1
Accessions EAW97081 EAW97082 EAW97083 EAW97084 EAW97085 EAW97086 EAW97087 EAW97088 EAW97089 O14595 AF000152 AAB71816 AF022231 AAD09331 AK226076 AK291289 BAF83978 AK294930 BAG58009 AK310183 AK310873 AK311070 AK312413 AY279531 AAP34399 BC018922 BC065920 AAH65920 CN313995 DB001093 HQ448049 ADQ32530 U81556 AAB39318 XM_005268556 XP_005268613 NM_005730 NP_005721
Function Preferentially catalyzes the dephosphorylation of 'Ser- 5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas. {ECO:0000269|PubMed:12721286, ECO:0000269|PubMed:15681389}.
Subcellular Location Nucleus {ECO:0000250}.
Tissue Specificity Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver. {ECO:0000269|PubMed:15681389}.

OS4 (C-19) - sc-69518 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

OS4 (H-50) - sc-292617 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal

OS4 (N-17) - sc-69521 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

OS4 (2230C1a) - sc-81347 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
OS4 (2230C1a): sc-81347 Western Blot analysis of human recombinant OS4 fusion protein.

Anti-CTDSP2 antibody - ab60235 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Ab60235 (1/50-1/100) staining human CTDSP2 in human breast carcinoma tissue by immunohistochemistry using formalin fixed, paraffin embedded tissue. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma tissue.

Anti-CTDSP2 antibody - ab123370 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-CTDSP2 antibody (ab123370) at 1/100 dilution + 293 cell line lysates at 35 µg

Anti-CTDSP2 antibody [2230C1a] - ab50621 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2230C1a
Anti-CTDSP2 antibody [2230C1a] (ab50621) + recombinant CTDSP2 fragment

Anti-CTDSP2 Antibody (aa10-39, AP) - LS-C255621 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody (aa10-39, APC) - LS-C255622 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody (aa10-39, Biotin) - LS-C255623 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody (aa10-39, FITC) - LS-C255624 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody (aa10-39, PE) - LS-C255626 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody (aa10-39, Azide-free, HRP) - LS-C255627 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody - LS-C307118 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CTDSP2 Antibody (N-Terminus) - LS-C111371 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSP2 antibody LS-C111371 Western blot of Fetal Kidney lysate.

Anti-CTDSP2 Antibody - LS-C311079 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody (aa10-39) - LS-C320659 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-CTDSP2 Antibody (aa10-39) - LS-C167123 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSP2 Antibody western blot of 293 cell line lysates (35 ug/lane). The CTDSP2 antibody detected the CTDSP2 protein (arrow).

Anti-CTDSP2 Antibody (clone 2230C1a) - LS-C342430 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2230C1a
Western blot analysis of immunized recombinant protein, using anti-CTDSP2 monoclonal antibody.

Anti-CTDSP2 Antibody (aa26-271) - LS-C185670 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
CTDSP2 antibody detects CTDSP2 protein by Western blot analysis. A. 30 ug PC-12 whole cell lysate/extract. 12 % SDS-PAGE. CTDSP2 antibody dilution:1:1000

Anti-CTDSP2 Antibody (N-Terminus) - LS-C101053 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Anti-CTDSP2 Antibody (C-Terminus) IHC-plus™ - LS-B11519 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE)

Anti-CTDSP2 Antibody (C-Terminus) - LS-C63950 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-CTDSP2 Antibody (clone 2230C1a) - LS-C184381 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal
Clone 2230C1a

SCP2 Antibody - NBP1-85958 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: SCP2 Antibody [NBP1-85958] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11. Lane 2: Human cell line RT-506
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