Gene Symbol | FUOM |
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Entrez Gene | 282969 |
Alt Symbol | C10orf125, FUCU, FucM |
Species | Human |
Gene Type | protein-coding |
Description | fucose mutarotase |
Other Description | protein fucU homolog |
Swissprots | Q5VWY2 A1L300 A2VDF0 Q6ZPD2 Q5VWY3 |
Accessions | A2VDF0 EAW61337 EAW61338 AI333356 AK129527 BAC85178 AK310070 BC129818 AAI29819 BC129819 AAI29820 BM009909 BU849497 BX119427 CN368132 HY163253 XM_011539670 XP_011537972 XM_011539671 XP_011537973 XM_011539672 XP_011537974 XM_011539673 XP_011537975 XM_011539674 XP_011537976 XM_011539675 XP_011537977 NM_001098483 NP_001091953 NM_001301827 NP_001288756 NM_001301828 NP_001288757 NM_198472 NP_940874 |
Function | Involved in the interconversion between alpha- and beta- L-fucoses. L-Fucose (6-deoxy-L-galactose) exists as alpha-L-fucose (29.5%) and beta-L-fucose (70.5%), the beta-form is metabolized through the salvage pathway. GDP-L-fucose formed either by the de novo or salvage pathways is transported into the endoplasmic reticulum, where it serves as a substrate for N- and O- glycosylations by fucosyltransferases. Fucosylated structures expressed on cell surfaces or secreted in biological fluids are believed to play a critical role in cell-cell adhesion and recognition processes. {ECO:0000269|PubMed:17602138}. |
FucU CRISPR/Cas9 KO Plasmid (h) - sc-415284 from Santa Cruz Biotechnology
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FucU HDR Plasmid (h) - sc-415284-HDR from Santa Cruz Biotechnology
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FucU Double Nickase Plasmid (h) - sc-415284-NIC from Santa Cruz Biotechnology
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FucU Double Nickase Plasmid (h2) - sc-415284-NIC-2 from Santa Cruz Biotechnology
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FucU CRISPR Activation Plasmid (h) - sc-415284-ACT from Santa Cruz Biotechnology
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FucU CRISPR Activation Plasmid (h2) - sc-415284-ACT-2 from Santa Cruz Biotechnology
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FucU Lentiviral Activation Particles (h) - sc-415284-LAC from Santa Cruz Biotechnology
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FucU Lentiviral Activation Particles (h2) - sc-415284-LAC-2 from Santa Cruz Biotechnology
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FucU siRNA (h) - sc-90452 from Santa Cruz Biotechnology
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FucU shRNA Plasmid (h) - sc-90452-SH from Santa Cruz Biotechnology
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FucU shRNA (h) Lentiviral Particles - sc-90452-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU120971 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN4140 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4140 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR02438 from Sigma-Aldrich
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FUOM siRNA (Human) - CRJ6856 from Cohesion Biosciences
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FUOM - MBS8205558 from MyBioSource
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shRNA set against Human C10orf125 (NM_198472.2) - SHH248638 from Creative biogene
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FUOM shRNA Plasmid (Human) - CHJ6856 from Cohesion Biosciences
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FUOM miRNA 3'UTR clone - MiUTR1H-00996 from Creative biogene
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