Gene Symbol | H2AFV |
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Entrez Gene | 94239 |
Alt Symbol | H2A.Z-2, H2AV |
Species | Human |
Gene Type | protein-coding |
Description | H2A histone family, member V |
Other Description | H2A.F/Z|histone H2A.F/Z|histone H2A.V|purine-rich binding element protein B |
Swissprots | Q59GV8 A6NFA8 Q6PK98 A8MQC5 A6NKY0 A6NN01 Q71UI9 |
Accessions | AAS00365 EAW61074 EAW61075 EAW61076 EAW61077 Q71UI9 AB209001 BAD92238 AF081192 AAC31938 AK023973 BAG51243 AK025785 AK129989 AL049324 AL520785 AL520811 BC000098 AAH00098 BC004274 AAH04274 BC014885 AAH14885 BC070169 AAH70169 BF242439 BG679983 BG754026 BG773256 BI257891 BM452844 BM453663 BM850777 BX644511 CB148943 DA456475 DB460745 DQ892406 ABM83332 DQ895618 ABM86544 NM_012412 NP_036544 NM_138635 NP_619541 NM_201436 NP_958844 NM_201516 NP_958924 NM_201517 NP_958925 |
Function | Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000250}. Chromosome {ECO:0000250}. |
Top Pathways | Systemic lupus erythematosus, Alcoholism |
Anti-H2AFV Antibody (N-Terminus) - LS-C169985 from LifeSpan Bioscience
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Anti-H2AFV Antibody (clone 2F9) - LS-C134118 from LifeSpan Bioscience
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H2AFV Antibody - NBP2-14980 from Novus Biologicals
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H2AFV Antibody (2F9) - H00094239-M08 from Novus Biologicals
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Monoclonal Anti-H2AFV antibody produced in mouse - SAB1402651 from Sigma-Aldrich
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Anti-H2AFV antibody produced in rabbit - SAB2700247 from Sigma-Aldrich
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H2AFV Antibody - C-terminal region (ARP67545_P050) - ARP67545_P050 from Aviva Systems Biology
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H2AFV Antibody - N-terminal region (ARP67546_P050) - ARP67546_P050 from Aviva Systems Biology
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h2afv antibody - zf124658 from GeneTex
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Histone H2A.V antibody - GTX102073 from GeneTex
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Anti -H2AFV (Histone H2A.V, H2A.F/Z, H2AV, MGC10170, MGC10831, MGC1947, FLJ26479) - 127692 from USBiological Life Science
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Anti -H2AFV (Histone H2A.V, H2A.F/Z, H2AV, MGC10170, MGC10831, MGC1947, FLJ26479) (AP) - 127692-AP from USBiological Life Science
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Anti -H2AFV (Histone H2A.V, H2A.F/Z, H2AV, MGC10170, MGC10831, MGC1947, FLJ26479) (Biotin) - 127692-Biotin from USBiological Life Science
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Anti -H2AFV (Histone H2A.V, H2A.F/Z, H2AV, MGC10170, MGC10831, MGC1947, FLJ26479) (FITC) - 127692-FITC from USBiological Life Science
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Anti -H2AFV (Histone H2A.V, H2A.F/Z, H2AV, MGC10170, MGC10831, MGC1947, FLJ26479) (HRP) - 127692-HRP from USBiological Life Science
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Anti -H2AFV (Histone H2A.V, H2A.F/Z, H2AV, MGC10170, MGC10831, MGC1947, FLJ26479) (PE) - 127692-PE from USBiological Life Science
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Histone H2A.V antibody - orb184152 from Biorbyt
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Histone H2A.v antibody - H00094239-M08 from Acris Antibodies
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Mouse Anti-Human H2AFV - 101-10684 from RayBiotech
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H2AFV antibody - 15160-1-AP from Proteintech Group
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H2AFV antibody - 15580-1-AP from Proteintech Group
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H2AFV Antibody - EPP13804 from Elabscience
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H2AFV Antibody - EPP13805 from Elabscience
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Anti-H2AFV (aa 1-30) polyclonal antibody - DPABH-11658 from Creative Diagnostics
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Monoclonal Antibody to H2A Histone Family, Member V (H2AFV) - MAJ708Hu21 from Uscn Life Science Inc.
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