| Gene Symbol | POP7 |
|---|---|
| Entrez Gene | 10248 |
| Alt Symbol | 0610037N12Rik, RPP2, RPP20 |
| Species | Human |
| Gene Type | protein-coding |
| Description | processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae) |
| Other Description | POP7 (processing of precursor, S. cerevisiae) homolog|RNaseP protein p20|hPOP7|processing of precursor 7, ribonuclease P subunit|ribonuclease P protein subunit p20|ribonucleases P/MRP protein subunit POP7 homolog |
| Swissprots | A4D2E0 O75817 Q9BV74 |
| Accessions | EAL23821 EAW76495 O75817 AJ572668 BC001430 AAH01430 BI666854 U94316 AAC24113 NM_005837 NP_005828 |
| Function | Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences. |
| Subcellular Location | Nucleus, nucleolus {ECO:0000269|PubMed:14715275}. Cytoplasm {ECO:0000269|PubMed:14715275}. Cytoplasmic granule {ECO:0000269|PubMed:14715275}. Note=Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules. |
| Top Pathways | RNA transport, Ribosome biogenesis in eukaryotes |