| Gene Symbol |
POP7
|
| Entrez Gene |
10248
|
| Alt Symbol |
0610037N12Rik, RPP2, RPP20
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
processing of precursor 7, ribonuclease P/MRP subunit (S. cerevisiae)
|
| Other Description |
POP7 (processing of precursor, S. cerevisiae) homolog|RNaseP protein p20|hPOP7|processing of precursor 7, ribonuclease P subunit|ribonuclease P protein subunit p20|ribonucleases P/MRP protein subunit POP7 homolog
|
| Swissprots |
A4D2E0 O75817 Q9BV74
|
| Accessions |
EAL23821 EAW76495 O75817 AJ572668 BC001430 AAH01430 BI666854 U94316 AAC24113 NM_005837 NP_005828
|
| Function |
Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of RNase MRP complex, which cleaves pre-rRNA sequences.
|
| Subcellular Location |
Nucleus, nucleolus {ECO:0000269|PubMed:14715275}. Cytoplasm {ECO:0000269|PubMed:14715275}. Cytoplasmic granule {ECO:0000269|PubMed:14715275}. Note=Under stress conditions colocalizes with SMN1 in punctuated cytoplasmic granules.
|
| Top Pathways |
RNA transport, Ribosome biogenesis in eukaryotes
|
![Western Blot: POP7 Overexpression Lysate (Adult Normal) [NBP2-07694] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for POP7.](http://www.bioprodhub.com/system/product_images/cel_products/5/sub_2/8237_POP7%2520Overexpression%2520Lysate%2520(Adult%2520Normal)-Western%2520Blot-NBP2-07694-img0001.jpg)