| Gene Symbol | Npr1 |
|---|---|
| Entrez Gene | 18160 |
| Alt Symbol | AI893888, GC-A, NPR-A, NPRA, Pndr |
| Species | Mouse |
| Gene Type | protein-coding |
| Description | natriuretic peptide receptor 1 |
| Other Description | ANP-A|ANPR-A|Nppa receptor|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor type A|guanylate cyclase A|guanylyl cyclase-A |
| Swissprots | P18293 |
| Accessions | CAC41350 EDL15140 P18293 AK135008 BAE22383 BC110659 AAI10660 BC139767 CJ065787 J05504 AAA37670 L31932 AAA66945 XM_006501114 XP_006501177 XR_375494 NM_008727 NP_032753 |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand. |
| Subcellular Location | Membrane; Single-pass type I membrane protein. |
| Top Pathways | Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism |