| Gene Symbol |
Npr1
|
| Entrez Gene |
18160
|
| Alt Symbol |
AI893888, GC-A, NPR-A, NPRA, Pndr
|
| Species |
Mouse
|
| Gene Type |
protein-coding
|
| Description |
natriuretic peptide receptor 1
|
| Other Description |
ANP-A|ANPR-A|Nppa receptor|atrial natriuretic peptide receptor 1|atrial natriuretic peptide receptor type A|guanylate cyclase A|guanylyl cyclase-A
|
| Swissprots |
P18293
|
| Accessions |
CAC41350 EDL15140 P18293 AK135008 BAE22383 BC110659 AAI10660 BC139767 CJ065787 J05504 AAA37670 L31932 AAA66945 XM_006501114 XP_006501177 XR_375494 NM_008727 NP_032753
|
| Function |
Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
|
| Subcellular Location |
Membrane; Single-pass type I membrane protein.
|
| Top Pathways |
Vascular smooth muscle contraction, Oxytocin signaling pathway, cGMP-PKG signaling pathway, cAMP signaling pathway, Purine metabolism
|