SHFM1

Gene Symbol SHFM1
Entrez Gene 7979
Alt Symbol DSS1, ECD, SEM1, SHFD1, SHSF1, Shfdg1
Species Human
Gene Type protein-coding
Description split hand/foot malformation (ectrodactyly) type 1
Other Description 26S proteasome complex subunit DSS1|deleted in split hand/split foot protein 1|deleted in split-hand/split-foot 1|split hand/foot deleted protein 1|split hand/foot malformation type 1 protein
Swissprots P60896
Accessions AAQ93368 EAL24125 EAW76746 EAW76747 P60896 AK094899 AK291070 BAF83759 AK309241 BC032782 AAH32782 CR456887 CAG33168 U41515 AAA91179 NM_006304 NP_006295
Function Subunit of the 26S proteasome which plays a role in ubiquitin-dependent proteolysis (PubMed:15117943). Component of the TREX-2 complex (transcription and export complex 2), composed of at least ENY2, GANP, PCID2, DSS1, and either centrin CETN2 or CETN3 (PubMed:22307388). The TREX-2 complex functions in docking export-competent ribonucleoprotein particles (mRNPs) to the nuclear entrance of the nuclear pore complex (nuclear basket). TREX-2 participates in mRNA export and accurate chromatin positioning in the nucleus by tethering genes to the nuclear periphery. Binds and stabilizes BRCA2 and is thus involved in the control of R-loop-associated DNA damage and thus transcription- associated genomic instability. R-loop accumulation increases in DSS1-depleted cells. {ECO:0000269|PubMed:15117943, ECO:0000269|PubMed:22307388, ECO:0000269|PubMed:24896180}.
Tissue Specificity Expressed in limb bud, craniofacial primordia and skin.
Top Pathways Proteasome, Homologous recombination, Epstein-Barr virus infection

26S proteasome complex subunit DSS1 (SHFM1), Human, ELISA Kit - E01S0434 from ARP American Research Products

Category ELISA Kit
Prices $535.00, $735.00
Sizes 48 t, 96 t

26S proteasome complex subunit DSS1, ELISA Kit - MBS7217018 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7215679 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7248212 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7201109 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7236723 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7236752 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7214003 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7248580 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7217627 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7225831 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7250158 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

26S proteasome complex subunit DSS1 (SHFM1), ELISA Kit - MBS7221751 from MyBioSource

Category ELISA Kit
Prices $470.00, $675.00, $2,925.00, $5,490.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human ECD ELISA Kit - E012706 from Biobool

Category ELISA Kit

Human SEM1 ELISA Kit - E097550 from Biobool

Category ELISA Kit
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